U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C18H34O3
Molecular Weight 298.4608
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of IDROXIOLEIC ACID

SMILES

CCCCCCCC\C=C/CCCCCCC(O)C(O)=O

InChI

InChIKey=JBSOOFITVPOOSY-KTKRTIGZSA-N
InChI=1S/C18H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(19)18(20)21/h9-10,17,19H,2-8,11-16H2,1H3,(H,20,21)/b10-9-

HIDE SMILES / InChI

Approval Year

Name Type Language
IDROXIOLEIC ACID
INN  
Official Name English
2-OHOA
Common Name English
2-HYDROXYOLEIC ACID
Systematic Name English
idroxioleic acid [INN]
Common Name English
NFX88
Code English
9-OCTADECENOIC ACID, 2-HYDROXY-, (9Z)-
Systematic Name English
(Z)-2-HYDROXYOCTADEC-9-ENOIC ACID
Systematic Name English
NFX-88
Code English
ALPHA-HYDROXYOLEIC ACID
Systematic Name English
SML-0256
Code English
CIS-2-HYDROXY-9-OCTADECENOIC ACID
Systematic Name English
2-hydroxyoleic acid [WHO-DD]
Common Name English
MINERVAL
Common Name English
SML0256
Code English
RAC-(2R,9Z)-2-HYDROXYOCTADEC-9-ENOIC ACID
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 844021
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
EU-Orphan Drug EU/3/11/916
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
NCI_THESAURUS C274
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID00430863
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY
PUBCHEM
9796304
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY
INN
11607
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY INN
NCI_THESAURUS
C105401
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY NCIT
CAS
56472-29-8
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY
SMS_ID
100000181927
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY
EVMPD
SUB195753
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY
CHEBI
143096
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY
MANUFACTURER PRODUCT INFORMATION
2-HYDROXYOLEIC ACID
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY Biochem/physiol Actions: 2OHOA induces cell cycle arrest and apoptosis in several cancer cell lines, including glioma, leukemia, breast and colon cancer lines. 2OHOA increases sphingomyelin (SM) levels in the membranes of tumor cells, which typically display decreased SM membrane content, and remodeled membranes, compared with normal cells. The compound has no effect on SM levels in non-cancer cells.
FDA UNII
OSV3KVO1BT
Created by admin on Sat Dec 16 11:37:15 GMT 2023 , Edited by admin on Sat Dec 16 11:37:15 GMT 2023
PRIMARY