Gamcemetinib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H20ClN5O3S
Molecular Weight	469.944
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOCC1=C(OC2=CC=C3C4=C(SC5=C4NC[C@@H](C)NC5=O)C=CC3=N2)N=C(Cl)N=C1

InChI

InChIKey=PYOQIOLRFIRRSO-LLVKDONJSA-N

InChI=1S/C22H20ClN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

Gamcemetinib

Official Name

English

8H-[1,4]Diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, 3-[[2-chloro-5-(ethoxymethyl)-4-pyrimidinyl]oxy]-9,10,11,12-tetrahydro-10-methyl-, (10R)-

Common Name

English

BMS-986371

Code

English

gamcemetinib [INN]

Common Name

English

GAMCEMETINIB [USAN]

Common Name

English

(10R)-3-{[2-chloro-5-(ethoxymethyl)pyrimidin-4-yl]oxy}-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5′,6′:4,5]thieno[3,2-f]quinolin-8-one

Systematic Name

English

CC-99677

Code

English

Code System Code Type Description

INN

12796