BROMINDIONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H9BrO2
Molecular Weight	301.135
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

BrC1=CC=C(C=C1)C2C(=O)C3=CC=CC=C3C2=O

InChI

InChIKey=NPUZIGSOEWMFKK-UHFFFAOYSA-N

InChI=1S/C15H9BrO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13749480 | https://www.medchemexpress.com/Bromindione.html |

Bromindione is an oral anti-coagulant derived from the monobromination of the familiar phenylindandione (Hedulin, Danilone, Dindevan).

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Blood clotting 6 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13749480	Primary		Not Provided 511	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.	2013-09-05	23769903
Further studies of bromindione, a newer anticoagulant.	1967-07	4963164
Study of bromindione, a new anticoagulant.	1962-01-13	13913300
p-Bromindione: a new, potent, long-acting oral anticoagulant drug.	1961-09-09	13749480
[Anticoagulant effect of 2-(4-bromo) phenyl-1, 3-indandione (fluidemin)].	1956-10-15	13387072

Patents

Sample Use Guides

In Vivo Use Guide

The dose range used for oral Bromindione is between 5 mg to 40 mg, with the most common dosing regime of 10 or 15 mg.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

NSC-759118

Preferred Name

English

BROMINDIONE

Official Name

English

BROMINDIONE [USAN]

Common Name

English

BROMINDIONE [MI]

Common Name

English

bromindione [INN]

Common Name

English

1H-INDENE-1,3(2H)-DIONE, 2-(4-BROMOPHENYL)-

Systematic Name

English

2-(P-BROMOPHENYL)-1,3-INDANDIONE

Common Name

English

Code System Code Type Description

CAS

1146-98-1