Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C11H11BrN2S |
| Molecular Weight | 283.187 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
BrC1=CC=C(C=C1)[C@H]2CN3CCSC3=N2
InChI
InChIKey=HTHGAIADRJRJOY-SNVBAGLBSA-N
InChI=1S/C11H11BrN2S/c12-9-3-1-8(2-4-9)10-7-14-5-6-15-11(14)13-10/h1-4,10H,5-7H2/t10-/m1/s1
DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/455643
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/455643
(-)-p-Bromotetramisole is an inhibitor of non-specific alkaline phosphatase. L-p-Bromotetramisole shows no inhibition of specific phosphatase activity, and the D-enantiomer shows no inhibitory effects against either phosphatase. L-p-Bromotetramisole is used as a tool inhibitor in studies of tissue distribution of alkaline phosphatases.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Use of specific inhibitors to disciminate alkaline phosphatase isoenzymes originating from human liver, placenta and intestine: absence of meconial alkaline phosphatase in maternal serum. | 1979-07 |
|
| Tetramisole analogues as inhibitors of alkaline phosphatase, an enzyme involved in the resistance of neoplastic cells to 6-thiopurines. | 1977-04 |
|
| The inhibition of alkaline phosphatase by L-p-bromotetramisole. | 1975-08-28 |
Patents
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| Code System | Code | Type | Description | ||
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OEN33FEM7H
Created by
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56943-06-7
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DTXSID10350780
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admin on Mon Mar 31 23:20:50 GMT 2025 , Edited by admin on Mon Mar 31 23:20:50 GMT 2025
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688042
Created by
admin on Mon Mar 31 23:20:50 GMT 2025 , Edited by admin on Mon Mar 31 23:20:50 GMT 2025
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SUBSTANCE RECORD
