DIPROFENE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H29NOS
Molecular Weight	355.537
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCN(CCC)CCSC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=WEXRVFDKZKSKQS-UHFFFAOYSA-N

InChI=1S/C22H29NOS/c1-3-15-23(16-4-2)17-18-25-22(24)21(19-11-7-5-8-12-19)20-13-9-6-10-14-20/h5-14,21H,3-4,15-18H2,1-2H3

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Description
Sources: https://www.vidal.ru/drugs/molecule/1754 | https://www.rlsnet.ru/mnn_index_id_894.htm | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 456, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Diprofene is a myotropic antispasmodic with pronounced vasodilating effect. It has minor anticholinergic and local anesthetic properties. Antispasmodic action develops gradually. Diprofene is indicated for the treatment of peripheral vasospasms (obliterating endarteritis, Raynaud's disease, etc.) and spasm of smooth muscles of internal organs (gastric colic, intestinal colic, renal colic, biliary colic). Adverse effects are: dizziness, headache, nausea, numbness of the oral mucosa.

Approval Year

Sample Use Guides

In Vivo Use Guide

0,025 g twice a day during the month

Route of Administration: Oral

Name

Type

Language

DIPROFENE

Official Name

English

2-DIPROPYLAMINOETHYL DIPHENYLTHIOACETATE

Systematic Name

English

diprofene [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257