Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H10Cl2N2O |
Molecular Weight | 305.159 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC2=C(NC(=O)CN=C2C3=C(Cl)C=CC=C3)C=C1
InChI
InChIKey=CHIFCDOIPRCHCF-UHFFFAOYSA-N
InChI=1S/C15H10Cl2N2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
Delorazepam is a benzodiazepine with anxiolytic effects. It is a metabolite of the designer drug diclazepam that can be detected in either the serum or urine. Delorazepam can also be produced by enzymatic treatment of lorazepam with β-glucuronidase. It is indicated for the treatment of anxiety, tension and other somatic or psychiatric manifestations associated with anxiety syndrome, insomnia. The side effects and precautions for use of delorazepam are the same as for all benzodiazepines, in particular as regards the development of dependence (mental and physical) and tolerance. Prolonged use may lead to difficulties remembering recent names and events (anterograde amnesia). It has been approved for marketing in Italy.
Approval Year
PubMed
Title | Date | PubMed |
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Participation of GABAergic mechanisms in the hypotensive and bradycardic effects of clonidine: experimental study in conscious normotensive and hypertensive rats. | 1987 Oct |
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An observational study in psychiatric acute patients admitted to General Hospital Psychiatric Wards in Italy. | 2007 Jan 27 |
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DEA NO. |
2754
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NCI_THESAURUS |
C1012
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C98132
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DELORAZEPAM
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111762
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SUB06957MIG
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100000090622
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220-771-9
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169895
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2894-67-9
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O91W32476G
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DB01511
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CHEMBL268254
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C013434
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DTXSID70183137
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4510
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17925
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800
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ACTIVE MOIETY