Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H19NOS |
| Molecular Weight | 297.415 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNCC[C@H](OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3
InChI
InChIKey=ZEUITGRIYCTCEM-KRWDZBQOSA-N
InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1
DescriptionSources: http://www.drugbank.ca/drugs/DB00476Curator's Comment: Description was created based on several sources, including
https://www.drugs.com/pro/cymbalta.html
Sources: http://www.drugbank.ca/drugs/DB00476
Curator's Comment: Description was created based on several sources, including
https://www.drugs.com/pro/cymbalta.html
Duloxetine (brand names Cymbalta, Yentreve, and in parts of Europe, Xeristar or Ariclaim) is indicated for the acute and maintenance treatment of major depressive disorder (MDD), as well as acute management of generalized anxiety disorder. Also used for the management of neuropathic pain associated with diabetic peripheral neuropathy, and fibromyalgia. Has been used in the management of moderate to severe stress urinary incontinence (SUI) in women. It is manufactured and marketed by Eli Lilly and Company. Duloxetine has not yet been FDA approved for stress urinary incontinence or for fibromyalgia. Duloxetine is a selective SNRI (selective serotonin-norepinephrine reuptake inhibitor). Duloxetine is a systemic drug therapy which affects the body as a whole. Known also under the code name LY248686, it is a potent dual reuptake inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE), possessing comparable affinities in binding to NE- and 5-HT transporter sites. It is a less potent inhibitor of dopamine reuptake.
CNS Activity
Originator
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL228 |
10.4 nM [IC50] | ||
Target ID: CHEMBL222 |
1.58 nM [IC50] | ||
Target ID: CHEMBL240 |
142.8 µM [IC50] |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | Cymbalta Approved UseCymbalta® is indicated for the treatment of:
Major Depressive Disorder
Generalized Anxiety Disorder
Diabetic Peripheral Neuropathy
Fibromyalgia
Chronic Musculoskeletal Pain Launch Date2004 |
|||
| Primary | Cymbalta Approved UseCymbalta® is indicated for the treatment of:
Major Depressive Disorder
Generalized Anxiety Disorder
Diabetic Peripheral Neuropathy
Fibromyalgia
Chronic Musculoskeletal Pain Launch Date2004 |
|||
| Palliative | Cymbalta Approved UseCymbalta® is indicated for the treatment of:
Major Depressive Disorder
Generalized Anxiety Disorder
Diabetic Peripheral Neuropathy
Fibromyalgia
Chronic Musculoskeletal Pain Launch Date2004 |
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
55.88 μg/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
60 mg single, oral dose: 60 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
0.44 μg/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
15 mg single, oral dose: 15 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
31.82 μg/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
43.09 μg/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
30 mg 1 times / day multiple, oral dose: 30 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
1073.99 μg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
60 mg single, oral dose: 60 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
175.39 μg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
15 mg single, oral dose: 15 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
489.35 μg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
840.26 μg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
30 mg 1 times / day multiple, oral dose: 30 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
11.89 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
60 mg single, oral dose: 60 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
9.52 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
15 mg single, oral dose: 15 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
10.19 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
30 mg single, oral dose: 30 mg route of administration: Oral experiment type: SINGLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
|
11.39 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/23678352 |
30 mg 1 times / day multiple, oral dose: 30 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
DULOXETINE plasma | Homo sapiens population: HEALTHY age: ADULT sex: UNKNOWN food status: FASTED |
Funbound
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
10% |
DULOXETINE plasma | Homo sapiens population: UNKNOWN age: UNKNOWN sex: UNKNOWN food status: UNKNOWN |
Doses
| Dose | Population | Adverse events |
|---|---|---|
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 2327 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 17 - 89 Sex: M+F Population Size: 2327 Sources: |
Disc. AE: Nausea... AEs leading to discontinuation/dose reduction: Nausea (1.3%) Sources: |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 568 Health Status: unhealthy Condition: Diabetic Peripheral Neuropathic Pain Age Group: 17 - 89 Sex: M+F Population Size: 568 Sources: |
Disc. AE: Nausea, Dizziness... AEs leading to discontinuation/dose reduction: Nausea (3.5%) Sources: Dizziness (1.6%) Somnolence (1.6%) Fatigue (1.1%) |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 668 Health Status: unhealthy Condition: Generalized Anxiety Disorder Age Group: 17 - 89 Sex: M+F Population Size: 668 Sources: |
Disc. AE: Nausea, Vomiting... AEs leading to discontinuation/dose reduction: Nausea (3.7%) Sources: Vomiting (1.3%) Dizziness (1%) |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 876 Health Status: unhealthy Condition: Fibromyalgia Age Group: 17 - 89 Sex: M+F Population Size: 876 Sources: |
Disc. AE: Nausea, Somnolence... AEs leading to discontinuation/dose reduction: Nausea (1.9%) Sources: Somnolence (1.5%) Fatigue (1.3%) |
2820 mg single, oral Overdose |
unhealthy, 25 n = 1 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 25 Sex: M Population Size: 1 Sources: |
Disc. AE: Generalized tonic-clonic seizure, Blurred vision... AEs leading to discontinuation/dose reduction: Generalized tonic-clonic seizure Sources: Blurred vision Irritability Anxiety |
120 mg 1 times / day multiple, oral Recommended Dose: 120 mg, 1 times / day Route: oral Route: multiple Dose: 120 mg, 1 times / day Sources: Page: p.459 |
unhealthy, 49.9 n = 82 Health Status: unhealthy Condition: Fibromyalgia Age Group: 49.9 Sex: M+F Population Size: 82 Sources: Page: p.459 |
Disc. AE: Dizziness, Pain... AEs leading to discontinuation/dose reduction: Dizziness (3%) Sources: Page: p.459Pain (3%) |
120 mg 1 times / day multiple, oral Recommended Dose: 120 mg, 1 times / day Route: oral Route: multiple Dose: 120 mg, 1 times / day Sources: Page: p.458 |
unhealthy, 51.5 n = 72 Health Status: unhealthy Condition: Fibromyalgia Age Group: 51.5 Sex: M+F Population Size: 72 Sources: Page: p.458 |
Disc. AE: Fatigue, Insomnia... AEs leading to discontinuation/dose reduction: Fatigue (4%) Sources: Page: p.458Insomnia (4%) |
4 mg single, oral Dose: 4 mg Route: oral Route: single Dose: 4 mg Sources: |
healthy, adult n = 83 Health Status: healthy Age Group: adult Sex: M Population Size: 83 Sources: |
Other AEs: Fatigue, Nausea... Other AEs: Fatigue (below serious, 2 patients) Sources: Nausea (below serious, 2 patients) Libido decreased (below serious, 1 patient) Stomach discomfort (below serious, 4 patients) |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
Other AEs: Syncope, Drug abuse... Other AEs: Syncope (serious, 1 patient) Sources: Drug abuse (serious, 1 patient) Panic attack (serious, 1 patient) Social phobia (serious, 1 patient) Diarrhoea (below serious, 6 patients) Nausea (below serious, 20 patients) Vomiting (below serious, 7 patients) Fatigue (below serious, 8 patients) Influenza (below serious, 7 patients) Upper respiratory tract infection (below serious, 4 patients) Decreased appetite (below serious, 10 patients) Dizziness (below serious, 10 patients) Headache (below serious, 19 patients) Somnolence (below serious, 7 patients) Insomnia (below serious, 6 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
Other AEs: Constipation, Diarrhoea... Other AEs: Constipation (below serious, 21 patient) Sources: Diarrhoea (below serious, 14 patients) Dry mouth (below serious, 33 patients) Nausea (below serious, 50 patients) Fatigue (below serious, 16 patients) Decreased appetite (below serious, 8 patients) Dizziness (below serious, 14 patients) Somnolence (below serious, 16 patients) Hyperhidrosis (below serious, 16 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 51 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 51 Sources: |
Other AEs: Prostate cancer, Ejaculation delayed... Other AEs: Prostate cancer (serious, 1 patient) Sources: Ejaculation delayed (below serious, 3 patients) Erectile dysfunction (below serious, 3 patients) |
60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
Disc. AE: Suicidal ideation, Suicidal behavior... AEs leading to discontinuation/dose reduction: Suicidal ideation Sources: Suicidal behavior Hepatic failure Orthostatic hypotension Syncope Serotonin syndrome Neuroleptic malignant syndrome Bleeding Mania Hypomania Seizures Hyponatremia Urinary hesitation Urinary retention |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
Other AEs: Myocardial infarction, Diarrhoea... Other AEs: Myocardial infarction (serious, 1 patient) Sources: Diarrhoea (serious, 1 patient) Hypoaesthesia oral (serious, 1 patient) Hypoaesthesia (serious, 1 patient) Transient ischaemic attack (serious, 1 patient) Palpitations (below serious, 3 patients) Vision blurred (below serious, 2 patients) Abdominal distension (below serious, 2 patients) Abdominal pain (below serious, 1 patient) Abdominal pain upper (below serious, 2 patients) Constipation (below serious, 14 patients) Diarrhoea (below serious, 7 patients) Dry mouth (below serious, 12 patients) Dyspepsia (below serious, 3 patients) Gastrooesophageal reflux disease (below serious, 2 patients) Nausea (below serious, 14 patients) Stomach discomfort (below serious, 2 patients) Vomiting (below serious, 3 patients) Asthenia (below serious, 3 patients) Fatigue (below serious, 10 patients) Irritability (below serious, 2 patients) Therapeutic response unexpected (below serious, 1 patient) Urinary tract infection (below serious, 2 patients) Anorexia (below serious, 3 patients) Decreased appetite (below serious, 5 patients) Hyperglycaemia (below serious, 1 patient) Hypokalaemia (below serious, 2 patients) Muscle spasms (below serious, 1 patient) Musculoskeletal pain (below serious, 2 patients) Pain in extremity (below serious, 2 patients) Dizziness (below serious, 9 patients) Headache (below serious, 10 patients) Hypersomnia (below serious, 1 patient) Hypoaesthesia (below serious, 1 patient) Lethargy (below serious, 2 patients) Paraesthesia (below serious, 2 patients) Sedation (below serious, 3 patients) Somnolence (below serious, 14 patients) Anorgasmia (below serious, 3 patients) Insomnia (below serious, 21 patient) Libido decreased (below serious, 4 patients) Loss of libido (below serious, 2 patients) Sleep disorder (below serious, 4 patients) Nocturia (below serious, 4 patients) Pollakiuria (below serious, 2 patients) Ejaculation delayed (below serious, 2 patients) Ejaculation disorder (below serious, 2 patients) Erectile dysfunction (below serious, 3 patients) Testicular pain (below serious, 2 patients) Pharyngolaryngeal pain (below serious, 2 patients) Yawning (below serious, 1 patient) Hyperhidrosis (below serious, 5 patients) Pruritus (below serious, 3 patients) Hot flush (below serious, 1 patient) Hypertension (below serious, 5 patients) |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
Other AEs: Wrist fracture, Osteoarthritis... Other AEs: Wrist fracture (serious, 1 patient) Sources: Osteoarthritis (serious, 2 patients) Encephalopathy hypertensive (serious, 1 patient) Transient ischaemic attack (serious, 1 patient) Tachycardia (below serious, 3 patients) Vertigo (below serious, 3 patients) Abdominal distension (below serious, 3 patients) Abdominal pain upper (below serious, 2 patients) Constipation (below serious, 6 patients) Diarrhoea (below serious, 8 patients) Dry mouth (below serious, 11 patient) Dyspepsia (below serious, 2 patients) Nausea (below serious, 14 patients) Vomiting (below serious, 2 patients) Asthenia (below serious, 2 patients) Fatigue (below serious, 8 patients) Influenza (below serious, 4 patients) Sinusitis (below serious, 2 patients) Weight increased (below serious, 2 patients) Anorexia (below serious, 2 patients) Neck pain (below serious, 3 patients) Dizziness (below serious, 7 patients) Dysgeusia (below serious, 2 patients) Migraine (below serious, 3 patients) Somnolence (below serious, 6 patients) Erectile dysfunction (below serious, 3 patients) Hyperhidrosis (below serious, 8 patients) |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
Other AEs: Gastrointestinal disorder (NOS), Sinus infection... Other AEs: Gastrointestinal disorder (NOS) (serious, 1 patient) Sources: Sinus infection (serious, 1 patient) Nausea (below serious, 9 patients) Dry mouth (below serious, 7 patients) Constipation (below serious, 5 patients) Hyperhidrosis (below serious, 5 patients) |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
Other AEs: Intervertebral disc protrusion, Constipation... Other AEs: Intervertebral disc protrusion (serious, 1 patient) Sources: Constipation (below serious, 35 patients) Diarrhoea (below serious, 27 patients) Dry mouth (below serious, 31 patient) Nausea (below serious, 83 patients) Vomiting (below serious, 12 patients) Fatigue (below serious, 25 patients) Decreased appetite (below serious, 13 patients) Dizziness (below serious, 26 patients) Headache (below serious, 45 patients) Somnolence (below serious, 15 patients) Insomnia (below serious, 24 patients) Hyperhidrosis (below serious, 23 patients) Hot flush (below serious, 13 patients) |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
Other AEs: Acute myocardial infarction, Vertigo... Other AEs: Acute myocardial infarction (serious, 1 patient) Sources: Vertigo (serious, 1 patient) Alcohol poisoning (serious, 1 patient) Myopathy toxic (serious, 1 patient) Asthma (serious, 1 patient) Tinnitus (below serious, 2 patients) Vertigo (below serious, 5 patients) Vision blurred (below serious, 2 patients) Constipation (below serious, 12 patients) Diarrhoea (below serious, 9 patients) Dry mouth (below serious, 13 patients) Flatulence (below serious, 3 patients) Nausea (below serious, 35 patients) Toothache (below serious, 2 patients) Asthenia (below serious, 2 patients) Fatigue (below serious, 7 patients) Hypertransaminasaemia (below serious, 2 patients) Nasopharyngitis (below serious, 5 patients) Viral infection (below serious, 2 patients) Joint sprain (below serious, 2 patients) Anorexia (below serious, 4 patients) Decreased appetite (below serious, 2 patients) Increased appetite (below serious, 2 patients) Muscle spasms (below serious, 2 patients) Neck pain (below serious, 2 patients) Dizziness (below serious, 10 patients) Headache (below serious, 27 patients) Migraine (below serious, 2 patients) Somnolence (below serious, 10 patients) Confusional state (below serious, 2 patients) Libido decreased (below serious, 4 patients) Urinary retention (below serious, 2 patients) Urine flow decreased (below serious, 2 patients) Ejaculation disorder (below serious, 2 patients) Sexual dysfunction (below serious, 2 patients) Yawning (below serious, 4 patients) Hyperhidrosis (below serious, 5 patients) Pruritus (below serious, 2 patients) |
120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
Other AEs: Palpitations, Vision blurred... Other AEs: Palpitations (below serious, 3 patients) Sources: Vision blurred (below serious, 3 patients) Abdominal discomfort (below serious, 7 patients) Constipation (below serious, 10 patients) Dry mouth (below serious, 10 patients) Nausea (below serious, 30 patients) Vomiting (below serious, 6 patients) Asthenia (below serious, 5 patients) Fatigue (below serious, 4 patients) Anorexia (below serious, 6 patients) Decreased appetite (below serious, 3 patients) Dizziness (below serious, 15 patients) Somnolence (below serious, 12 patients) Tremor (below serious, 4 patients) Hyperhidrosis (below serious, 7 patients) |
120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
Other AEs: Coronary artery disease, Urosepsis... Other AEs: Coronary artery disease (serious, 1 patient) Sources: Urosepsis (serious, 1 patient) Fall (serious, 1 patient) Metastases to central nervous system (serious, 1 patient) Syncope (serious, 1 patient) Palpitations (below serious, 4 patients) Vision blurred (below serious, 5 patients) Abdominal discomfort (below serious, 5 patients) Abdominal pain (below serious, 4 patients) Abdominal pain upper (below serious, 7 patients) Constipation (below serious, 23 patients) Diarrhoea (below serious, 18 patients) Dry mouth (below serious, 25 patients) Dyspepsia (below serious, 3 patients) Flatulence (below serious, 6 patients) Nausea (below serious, 41 patient) Vomiting (below serious, 11 patient) Fatigue (below serious, 18 patients) Feeling jittery (below serious, 3 patients) Thirst (below serious, 3 patients) Liver function test abnormal (below serious, 3 patients) Weight increased (below serious, 3 patients) Decreased appetite (below serious, 15 patients) Arthralgia (below serious, 6 patients) Dizziness (below serious, 17 patients) Dysgeusia (below serious, 4 patients) Headache (below serious, 16 patients) Somnolence (below serious, 14 patients) Tremor (below serious, 3 patients) Insomnia (below serious, 13 patients) Libido decreased (below serious, 5 patients) Dysuria (below serious, 3 patients) Pollakiuria (below serious, 6 patients) Urine flow decreased (below serious, 3 patients) Erectile dysfunction (below serious, 5 patients) Cough (below serious, 6 patients) Dermatitis contact (below serious, 3 patients) Hyperhidrosis (below serious, 10 patients) Night sweats (below serious, 4 patients) Rash (below serious, 3 patients) Hot flush (below serious, 4 patients) Hypertension (below serious, 3 patients) |
20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
Other AEs: Non-cardiac chest pain, Conjunctivitis... Other AEs: Non-cardiac chest pain (serious, 1 patient) Sources: Conjunctivitis (below serious, 2 patients) Vision blurred (below serious, 1 patient) Abdominal pain (below serious, 1 patient) Colonic polyp (below serious, 1 patient) Constipation (below serious, 2 patients) Dry mouth (below serious, 3 patients) Gastritis (below serious, 1 patient) Nausea (below serious, 11 patient) Stomach discomfort (below serious, 1 patient) Vomiting (below serious, 2 patients) Irritability (below serious, 2 patients) Non-cardiac chest pain (below serious, 1 patient) Therapeutic response unexpected (below serious, 1 patient) Drug hypersensitivity (below serious, 1 patient) Cystitis (below serious, 1 patient) Folliculitis (below serious, 1 patient) Gastroenteritis (below serious, 1 patient) Kidney infection (below serious, 1 patient) Pharyngitis (below serious, 4 patients) Tooth abscess (below serious, 1 patient) Urinary tract infection (below serious, 2 patients) Joint injury (below serious, 1 patient) Muscle strain (below serious, 1 patient) Neurological examination abnormal (below serious, 1 patient) Anorexia (below serious, 1 patient) Dehydration (below serious, 1 patient) Hyperglycaemia (below serious, 1 patient) Arthralgia (below serious, 2 patients) Back pain (below serious, 1 patient) Groin pain (below serious, 1 patient) Haemarthrosis (below serious, 1 patient) Muscle spasms (below serious, 1 patient) Musculoskeletal pain (below serious, 1 patient) Myalgia (below serious, 1 patient) Osteoarthritis (below serious, 1 patient) Aphonia (below serious, 1 patient) Dizziness (below serious, 3 patients) Hypersomnia (below serious, 1 patient) Somnolence (below serious, 3 patients) Confusional state (below serious, 1 patient) Dysphoria (below serious, 1 patient) Insomnia (below serious, 6 patients) Libido decreased (below serious, 2 patients) Breast cyst (below serious, 1 patient) Erectile dysfunction (below serious, 1 patient) Haemorrhage vaginal (below serious, 1 patient) Vulvovaginal pruritus (below serious, 1 patient) Asthma (below serious, 2 patients) Epistaxis (below serious, 1 patient) Nasal congestion (below serious, 1 patient) Acne (below serious, 1 patient) Generalised pruritus (below serious, 1 patient) Psoriasis (below serious, 1 patient) Cardiac ablation (below serious, 1 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
Other AEs: Arrhythmia, Atrial flutter... Other AEs: Arrhythmia (serious, 1 patient) Sources: Atrial flutter (serious, 1 patient) Coronary artery occlusion (serious, 1 patient) Pneumoperitoneum (serious, 1 patient) Chest pain (serious, 2 patients) Abscess intestinal (serious, 1 patient) Ankle fracture (serious, 1 patient) Head injury (serious, 1 patient) Hip fracture (serious, 1 patient) Diabetes mellitus (serious, 1 patient) Osteoarthritis spinal (serious, 1 patient) Oesophageal adenocarcinoma metastatic (serious, 1 patient) Intracranial aneurysm (serious, 1 patient) Renal failure acute (serious, 1 patient) Prostatitis (serious, 1 patient) Dyspnoea (serious, 1 patient) Interstitial lung disease (serious, 1 patient) Orthostatic hypotension (serious, 1 patient) Constipation (below serious, 37 patients) Diarrhoea (below serious, 31 patient) Dry mouth (below serious, 34 patients) Nausea (below serious, 28 patients) Fatigue (below serious, 14 patients) Upper respiratory tract infection (below serious, 13 patients) Contusion (below serious, 12 patients) Fall (below serious, 59 patients) Pain in extremity (below serious, 10 patients) Dizziness (below serious, 26 patients) Headache (below serious, 32 patients) Hyperhidrosis (below serious, 15 patients) Orthostatic hypotension (below serious, 5 patients) |
60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
Other AEs: Muscular weakness, Dizziness... Other AEs: Muscular weakness (serious, 1 patient) Sources: Dizziness (serious, 1 patient) Dyspnoea (serious, 1 patient) Palpitations (below serious, 3 patients) Vision blurred (below serious, 1 patient) Abdominal pain (below serious, 2 patients) Constipation (below serious, 10 patients) Diarrhoea (below serious, 10 patients) Dry mouth (below serious, 12 patients) Dyspepsia (below serious, 3 patients) Nausea (below serious, 24 patients) Vomiting (below serious, 2 patients) Fatigue (below serious, 7 patients) Feeling abnormal (below serious, 2 patients) Gastroenteritis (below serious, 3 patients) Influenza (below serious, 6 patients) Pharyngitis (below serious, 1 patient) Pharyngotonsillitis (below serious, 2 patients) Anorexia (below serious, 3 patients) Decreased appetite (below serious, 5 patients) Arthralgia (below serious, 5 patients) Muscle spasms (below serious, 1 patient) Myalgia (below serious, 2 patients) Pain in extremity (below serious, 3 patients) Dizziness (below serious, 9 patients) Headache (below serious, 12 patients) Hypoaesthesia (below serious, 4 patients) Lethargy (below serious, 1 patient) Paraesthesia (below serious, 2 patients) Sedation (below serious, 3 patients) Somnolence (below serious, 5 patients) Tremor (below serious, 2 patients) Confusional state (below serious, 1 patient) Insomnia (below serious, 10 patients) Libido decreased (below serious, 2 patients) Sleep disorder (below serious, 2 patients) Nocturia (below serious, 1 patient) Pollakiuria (below serious, 1 patient) Erectile dysfunction (below serious, 3 patients) Pharyngolaryngeal pain (below serious, 2 patients) Yawning (below serious, 2 patients) Hot flush (below serious, 5 patients) Hypertension (below serious, 3 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
Other AEs: Acute myocardial infarction, Panic attack... Other AEs: Acute myocardial infarction (serious, 1 patient) Sources: Panic attack (serious, 1 patient) Vision blurred (below serious, 4 patients) Nausea (below serious, 63 patients) Dry mouth (below serious, 40 patients) Diarrhoea (below serious, 19 patients) Constipation (below serious, 18 patients) Vomiting (below serious, 5 patients) Abdominal pain (below serious, 5 patients) Fatigue (below serious, 13 patients) Feeling jittery (below serious, 4 patients) Viral upper respiratory tract infection (below serious, 6 patients) Accidental overdose (below serious, 2 patients) Weight decreased (below serious, 4 patients) Blood pressure increased (below serious, 3 patients) Decreased appetite (below serious, 8 patients) Anorexia (below serious, 5 patients) Headache (below serious, 21 patient) Dizziness (below serious, 22 patients) Somnolence (below serious, 20 patients) Tension headache (below serious, 4 patients) Tremor (below serious, 4 patients) Insomnia (below serious, 11 patient) Restlessness (below serious, 5 patients) Libido decreased (below serious, 4 patients) Orgasm abnormal (below serious, 3 patients) Yawning (below serious, 3 patients) Hyperhidrosis (below serious, 11 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
Other AEs: Angina pectoris, Somnolence... Other AEs: Angina pectoris (serious, 1 patient) Sources: Somnolence (serious, 1 patient) Sexual abuse (serious, 1 patient) Nausea (below serious, 57 patients) Dry mouth (below serious, 25 patients) Constipation (below serious, 8 patients) Dyspepsia (below serious, 3 patients) Vomiting (below serious, 10 patients) Abdominal pain upper (below serious, 2 patients) Stomach discomfort (below serious, 2 patients) Fatigue (below serious, 15 patients) Feeling jittery (below serious, 4 patients) Influenza (below serious, 2 patients) Blood creatine phosphokinase increased (below serious, 1 patient) Decreased appetite (below serious, 11 patient) Headache (below serious, 26 patients) Somnolence (below serious, 18 patients) Dizziness (below serious, 17 patients) Tension headache (below serious, 2 patients) Libido decreased (below serious, 7 patients) Anorgasmia (below serious, 6 patients) Insomnia (below serious, 6 patients) Anxiety (below serious, 5 patients) Abnormal dreams (below serious, 4 patients) Hyperhidrosis (below serious, 8 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
Other AEs: Hernia inguinal, Clostridial infection... Other AEs: Hernia inguinal (serious, 1 patient) Sources: Clostridial infection (serious, 1 patient) Diverticulitis (serious, 1 patient) Respiratory tract infection (serious, 1 patient) Syncope (serious, 1 patient) Suicide attempt (serious, 1 patient) Vision blurred (below serious, 7 patients) Abdominal discomfort (below serious, 7 patients) Constipation (below serious, 17 patients) Diarrhoea (below serious, 15 patients) Dry mouth (below serious, 22 patients) Dyspepsia (below serious, 8 patients) Nausea (below serious, 51 patient) Vomiting (below serious, 7 patients) Fatigue (below serious, 11 patient) Decreased appetite (below serious, 13 patients) Dizziness (below serious, 13 patients) Headache (below serious, 30 patients) Somnolence (below serious, 24 patients) Anxiety (below serious, 8 patients) Insomnia (below serious, 11 patient) Yawning (below serious, 9 patients) Hyperhidrosis (below serious, 14 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
Other AEs: Non-cardiac chest pain, Constipation... Other AEs: Non-cardiac chest pain (serious, 1 patient) Sources: Constipation (below serious, 12 patients) Diarrhoea (below serious, 18 patients) Dry mouth (below serious, 30 patients) Nausea (below serious, 46 patients) Fatigue (below serious, 7 patients) Decreased appetite (below serious, 10 patients) Dizziness (below serious, 17 patients) Somnolence (below serious, 22 patients) Insomnia (below serious, 14 patients) Hyperhidrosis (below serious, 8 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
Other AEs: Nausea, Diarrhoea... Other AEs: Nausea (below serious, 12 patients) Sources: Diarrhoea (below serious, 10 patients) Dry mouth (below serious, 7 patients) Upper respiratory tract infection (below serious, 3 patients) Headache (below serious, 7 patients) Somnolence (below serious, 5 patients) Dizziness (below serious, 3 patients) Insomnia (below serious, 2 patients) Erectile dysfunction (below serious, 5 patients) Rash (below serious, 1 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
Other AEs: Palpitations, Vision blurred... Other AEs: Palpitations (below serious, 5 patients) Sources: Vision blurred (below serious, 6 patients) Nausea (below serious, 55 patients) Dry mouth (below serious, 26 patients) Diarrhoea (below serious, 19 patients) Constipation (below serious, 18 patients) Vomiting (below serious, 12 patients) Dyspepsia (below serious, 7 patients) Abdominal pain upper (below serious, 4 patients) Fatigue (below serious, 17 patients) Feeling jittery (below serious, 5 patients) Irritability (below serious, 4 patients) Viral upper respiratory tract infection (below serious, 5 patients) Urinary tract infection bacterial (below serious, 4 patients) Muscle strain (below serious, 3 patients) Decreased appetite (below serious, 15 patients) Muscle spasms (below serious, 2 patients) Headache (below serious, 28 patients) Dizziness (below serious, 24 patients) Somnolence (below serious, 12 patients) Dysgeusia (below serious, 5 patients) Sedation (below serious, 3 patients) Insomnia (below serious, 14 patients) Nightmare (below serious, 4 patients) Restlessness (below serious, 4 patients) Middle insomnia (below serious, 3 patients) Nervousness (below serious, 3 patients) Erectile dysfunction (below serious, 3 patients) Yawning (below serious, 4 patients) Rhinorrhoea (below serious, 3 patients) Hyperhidrosis (below serious, 8 patients) Hot flush (below serious, 2 patients) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 159 Health Status: unhealthy Condition: Fibromyalgia Population Size: 159 Sources: |
Other AEs: Menopausal symptoms, Metrorrhagia... Other AEs: Menopausal symptoms (below serious, 1 patient) Sources: Metrorrhagia (below serious, 1 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
Other AEs: Liver disorder, Anaemia... Other AEs: Liver disorder (serious, 1 patient) Sources: Anaemia (below serious, 1 patient) Palpitations (below serious, 5 patients) Vertigo (below serious, 4 patients) Vitreous floaters (below serious, 1 patient) Abdominal discomfort (below serious, 5 patients) Abdominal distension (below serious, 4 patients) Abdominal pain (below serious, 1 patient) Abdominal pain upper (below serious, 6 patients) Constipation (below serious, 29 patients) Diarrhoea (below serious, 8 patients) Dyspepsia (below serious, 2 patients) Food poisoning (below serious, 1 patient) Gastritis (below serious, 2 patients) Nausea (below serious, 42 patients) Stomatitis (below serious, 4 patients) Vomiting (below serious, 7 patients) Asthenia (below serious, 4 patients) Chest discomfort (below serious, 1 patient) Fatigue (below serious, 1 patient) Feeling abnormal (below serious, 2 patients) Malaise (below serious, 9 patients) Pyrexia (below serious, 2 patients) Thirst (below serious, 14 patients) Hepatic function abnormal (below serious, 5 patients) Bronchitis (below serious, 2 patients) Cystitis (below serious, 3 patients) Folliculitis (below serious, 1 patient) Hand-foot-and-mouth disease (below serious, 1 patient) Herpes zoster (below serious, 2 patients) Hordeolum (below serious, 1 patient) Influenza (below serious, 3 patients) Keratitis bacterial (below serious, 1 patient) Nasopharyngitis (below serious, 26 patients) Paronychia (below serious, 1 patient) Pertussis (below serious, 1 patient) Upper respiratory tract infection (below serious, 2 patients) Contusion (below serious, 3 patients) Heat illness (below serious, 1 patient) Alanine aminotransferase increased (below serious, 2 patients) Blood alkaline phosphatase increased (below serious, 2 patients) Blood bilirubin increased (below serious, 5 patients) Blood cholesterol increased (below serious, 2 patients) Blood uric acid increased (below serious, 1 patient) Haematocrit increased (below serious, 1 patient) Haemoglobin increased (below serious, 1 patient) Heart rate increased (below serious, 1 patient) Red blood cell count increased (below serious, 1 patient) Weight decreased (below serious, 2 patients) Decreased appetite (below serious, 13 patients) Arthritis (below serious, 1 patient) Musculoskeletal stiffness (below serious, 1 patient) Myalgia (below serious, 1 patient) Neck mass (below serious, 1 patient) Nodal osteoarthritis (below serious, 1 patient) Periarthritis (below serious, 1 patient) Fasciitis plantar (below serious, 1 patient) Synovial cyst (below serious, 1 patient) Tenosynovitis (below serious, 1 patient) Trigger finger (below serious, 2 patients) Autonomic nervous system imbalance (below serious, 1 patient) Dizziness (below serious, 11 patient) Dizziness postural (below serious, 2 patients) Dysgeusia (below serious, 1 patient) Dyskinesia (below serious, 1 patient) Head discomfort (below serious, 1 patient) Headache (below serious, 9 patients) Hypoaesthesia (below serious, 1 patient) Sensory disturbance (below serious, 1 patient) Sleep paralysis (below serious, 1 patient) Somnolence (below serious, 51 patient) Syncope (below serious, 1 patient) Tremor (below serious, 1 patient) Middle insomnia (below serious, 2 patients) Nightmare (below serious, 1 patient) Dysuria (below serious, 3 patients) Hypertonic bladder (below serious, 1 patient) Pollakiuria (below serious, 2 patients) Epistaxis (below serious, 1 patient) Hyperventilation (below serious, 1 patient) Oropharyngeal discomfort (below serious, 1 patient) Oropharyngeal pain (below serious, 1 patient) Allergic rhinitis (below serious, 1 patient) Yawning (below serious, 1 patient) Dermatitis atopic (below serious, 1 patient) Drug eruption (below serious, 1 patient) Hyperhidrosis (below serious, 2 patients) Miliaria (below serious, 1 patient) Pruritus (below serious, 5 patients) Purpura (below serious, 1 patient) Rash (below serious, 4 patients) Rash papular (below serious, 1 patient) Hot flush (below serious, 1 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
Other AEs: Craniocerebral injury, Subdural haematoma... Other AEs: Craniocerebral injury (serious, 1 patient) Sources: Subdural haematoma (serious, 1 patient) Nausea (below serious, 43 patients) Diarrhoea (below serious, 6 patients) Dry mouth (below serious, 16 patients) Decreased appetite (below serious, 12 patients) Headache (below serious, 24 patients) Dizziness (below serious, 11 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
Other AEs: Benign prostatic hyperplasia... Other AEs: Benign prostatic hyperplasia (below serious, 1 patient) Sources: |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 118 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 118 Sources: |
Other AEs: Atrophic vulvovaginitis... Other AEs: Atrophic vulvovaginitis (below serious, 1 patient) Sources: |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
Other AEs: Gastric polyps, Intervertebral disc protrusion... Other AEs: Gastric polyps (serious, 1 patient) Sources: Intervertebral disc protrusion (serious, 1 patient) Cerebral haemorrhage (serious, 1 patient) Calculus urethral (serious, 1 patient) Idiopathic thrombocytopenic purpura (below serious, 1 patient) Bundle branch block right (below serious, 1 patient) Tachycardia (below serious, 2 patients) Motion sickness (below serious, 1 patient) Tinnitus (below serious, 2 patients) Vertigo (below serious, 5 patients) Vertigo positional (below serious, 1 patient) Autoimmune thyroiditis (below serious, 1 patient) Conjunctivitis (below serious, 2 patients) Conjunctivitis allergic (below serious, 2 patients) Eye pain (below serious, 1 patient) Photophobia (below serious, 1 patient) Abdominal discomfort (below serious, 8 patients) Abdominal distension (below serious, 3 patients) Abdominal pain (below serious, 1 patient) Constipation (below serious, 25 patients) Dental caries (below serious, 4 patients) Diarrhoea (below serious, 9 patients) Dyspepsia (below serious, 4 patients) Gastritis (below serious, 2 patients) Atrophic gastritis (below serious, 1 patient) Gastrointestinal motility disorder (below serious, 1 patient) Gastrooesophageal reflux disease (below serious, 1 patient) Infrequent bowel movements (below serious, 1 patient) Large intestine polyp (below serious, 2 patients) Nausea (below serious, 21 patient) Altered saliva (below serious, 1 patient) Stomatitis (below serious, 2 patients) Vomiting (below serious, 1 patient) Face oedema (below serious, 1 patient) Feeling abnormal (below serious, 2 patients) Malaise (below serious, 8 patients) Oedema peripheral (below serious, 1 patient) Thirst (below serious, 14 patients) Hepatic function abnormal (below serious, 2 patients) Bronchitis (below serious, 7 patients) Gastroenteritis (below serious, 3 patients) Gingival abscess (below serious, 1 patient) Gingival infection (below serious, 1 patient) Pertussis (below serious, 1 patient) Pharyngitis (below serious, 3 patients) Bone contusion (below serious, 1 patient) Chillblains (below serious, 1 patient) Contusion (below serious, 16 patients) Excoriation (below serious, 1 patient) Fall (below serious, 1 patient) Ligament sprain (below serious, 5 patients) Nerve root injury cervical (below serious, 2 patients) Procedural pain (below serious, 4 patients) Spinal compression fracture (below serious, 1 patient) Thermal burn (below serious, 1 patient) Alanine aminotransferase increased (below serious, 4 patients) Aspartate aminotransferase increased (below serious, 3 patients) Blood creatine phosphokinase increased (below serious, 4 patients) Blood lactate dehydrogenase increased (below serious, 1 patient) Blood urea increased (below serious, 1 patient) Gamma-glutamyltransferase increased (below serious, 2 patients) Liver function test abnormal (below serious, 6 patients) White blood cell count increased (below serious, 1 patient) Decreased appetite (below serious, 10 patients) Arthralgia (below serious, 7 patients) Arthritis (below serious, 2 patients) Back pain (below serious, 4 patients) Fasciitis (below serious, 1 patient) Muscle spasms (below serious, 1 patient) Trigger finger (below serious, 1 patient) Carpal tunnel syndrome (below serious, 1 patient) Dizziness (below serious, 15 patients) Dizziness postural (below serious, 4 patients) Dysarthria (below serious, 1 patient) Headache (below serious, 9 patients) Hypoaesthesia (below serious, 1 patient) Migraine (below serious, 2 patients) Sciatica (below serious, 1 patient) Somnolence (below serious, 45 patients) Tension headache (below serious, 1 patient) Tremor (below serious, 4 patients) Anxiety (below serious, 1 patient) Dysphoria (below serious, 1 patient) Sleep talking (below serious, 1 patient) Chromaturia (below serious, 1 patient) Dysuria (below serious, 5 patients) Haematuria (below serious, 1 patient) Pollakiuria (below serious, 1 patient) Urinary retention (below serious, 1 patient) Urine flow decreased (below serious, 1 patient) Sexual dysfunction (below serious, 2 patients) Cough (below serious, 3 patients) Hyperventilation (below serious, 1 patient) Oropharyngeal pain (below serious, 1 patient) Allergic rhinitis (below serious, 2 patients) Eczema (below serious, 3 patients) Erythema (below serious, 1 patient) Hyperhidrosis (below serious, 1 patient) Pruritus (below serious, 3 patients) Rash macular (below serious, 1 patient) Swelling face (below serious, 1 patient) Hot flush (below serious, 1 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 53 Health Status: unhealthy Condition: Sub-Acute Pain Population Size: 53 Sources: |
Other AEs: Nausea, Somnolence... Other AEs: Nausea (below serious, 2 patients) Sources: Somnolence (below serious, 1 patient) SIADH (below serious, 1 patient) |
60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
Other AEs: Malignant ascites, Palpitations... Other AEs: Malignant ascites (serious, 1 patient) Sources: Palpitations (below serious, 1 patient) Ear congestion (below serious, 1 patient) Tinnitus (below serious, 1 patient) Vertigo positional (below serious, 1 patient) Basedow's disease (below serious, 1 patient) Blepharitis (below serious, 1 patient) Abdominal distension (below serious, 2 patients) Abdominal pain upper (below serious, 2 patients) Anal fissure (below serious, 1 patient) Cheilitis (below serious, 1 patient) Constipation (below serious, 19 patients) Dental caries (below serious, 1 patient) Diarrhoea (below serious, 6 patients) Dyspepsia (below serious, 1 patient) Faeces hard (below serious, 1 patient) Gastritis (below serious, 3 patients) Nausea (below serious, 18 patients) Stomatitis (below serious, 3 patients) Vomiting (below serious, 3 patients) Asthenia (below serious, 1 patient) Malaise (below serious, 12 patients) Peripheral swelling (below serious, 1 patient) Thirst (below serious, 19 patients) Hepatic function abnormal (below serious, 1 patient) Gingival abscess (below serious, 1 patient) Gingivitis (below serious, 1 patient) Hordeolum (below serious, 1 patient) Oral herpes (below serious, 1 patient) Paronychia (below serious, 1 patient) Tonsillitis (below serious, 1 patient) Chillblains (below serious, 1 patient) Contusion (below serious, 9 patients) Excoriation (below serious, 1 patient) Ligament sprain (below serious, 2 patients) Limb crushing injury (below serious, 1 patient) Muscle injury (below serious, 1 patient) Muscle rupture (below serious, 1 patient) Procedural pain (below serious, 1 patient) Alanine aminotransferase increased (below serious, 8 patients) Aspartate aminotransferase increased (below serious, 7 patients) Blood potassium decreased (below serious, 1 patient) Blood urine present (below serious, 3 patients) Liver function test abnormal (below serious, 1 patient) Decreased appetite (below serious, 9 patients) Diabetes mellitus (below serious, 1 patient) Intervertebral disc protrusion (below serious, 2 patients) Muscle spasms (below serious, 2 patients) Osteoporosis (below serious, 1 patient) Dizziness (below serious, 2 patients) Dizziness postural (below serious, 1 patient) Dysgeusia (below serious, 1 patient) Loss of consciousness (below serious, 1 patient) Migraine (below serious, 1 patient) Somnolence (below serious, 24 patients) Abulia (below serious, 1 patient) Depression (below serious, 1 patient) Insomnia (below serious, 3 patients) Dysuria (below serious, 2 patients) Hypertonic bladder (below serious, 1 patient) Stress urinary incontinence (below serious, 1 patient) Urethral haemorrhage (below serious, 1 patient) Urinary incontinence (below serious, 1 patient) Urine flow decreased (below serious, 1 patient) Cough (below serious, 1 patient) Upper respiratory tract inflammation (below serious, 3 patients) Dermatitis (below serious, 1 patient) Dermatitis contact (below serious, 2 patients) Eczema (below serious, 1 patient) Ingrowing nail (below serious, 1 patient) Dermatitis seborrhoeic (below serious, 1 patient) Hot flush (below serious, 1 patient) Hypertension (below serious, 1 patient) |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Nausea | 1.3% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 2327 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 17 - 89 Sex: M+F Population Size: 2327 Sources: |
| Fatigue | 1.1% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 568 Health Status: unhealthy Condition: Diabetic Peripheral Neuropathic Pain Age Group: 17 - 89 Sex: M+F Population Size: 568 Sources: |
| Dizziness | 1.6% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 568 Health Status: unhealthy Condition: Diabetic Peripheral Neuropathic Pain Age Group: 17 - 89 Sex: M+F Population Size: 568 Sources: |
| Somnolence | 1.6% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 568 Health Status: unhealthy Condition: Diabetic Peripheral Neuropathic Pain Age Group: 17 - 89 Sex: M+F Population Size: 568 Sources: |
| Nausea | 3.5% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 568 Health Status: unhealthy Condition: Diabetic Peripheral Neuropathic Pain Age Group: 17 - 89 Sex: M+F Population Size: 568 Sources: |
| Dizziness | 1% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 668 Health Status: unhealthy Condition: Generalized Anxiety Disorder Age Group: 17 - 89 Sex: M+F Population Size: 668 Sources: |
| Vomiting | 1.3% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 668 Health Status: unhealthy Condition: Generalized Anxiety Disorder Age Group: 17 - 89 Sex: M+F Population Size: 668 Sources: |
| Nausea | 3.7% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 668 Health Status: unhealthy Condition: Generalized Anxiety Disorder Age Group: 17 - 89 Sex: M+F Population Size: 668 Sources: |
| Fatigue | 1.3% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 876 Health Status: unhealthy Condition: Fibromyalgia Age Group: 17 - 89 Sex: M+F Population Size: 876 Sources: |
| Somnolence | 1.5% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 876 Health Status: unhealthy Condition: Fibromyalgia Age Group: 17 - 89 Sex: M+F Population Size: 876 Sources: |
| Nausea | 1.9% Disc. AE |
60 mg 2 times / day multiple, oral (max) Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy, 17 - 89 n = 876 Health Status: unhealthy Condition: Fibromyalgia Age Group: 17 - 89 Sex: M+F Population Size: 876 Sources: |
| Anxiety | Disc. AE | 2820 mg single, oral Overdose |
unhealthy, 25 n = 1 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 25 Sex: M Population Size: 1 Sources: |
| Blurred vision | Disc. AE | 2820 mg single, oral Overdose |
unhealthy, 25 n = 1 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 25 Sex: M Population Size: 1 Sources: |
| Generalized tonic-clonic seizure | Disc. AE | 2820 mg single, oral Overdose |
unhealthy, 25 n = 1 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 25 Sex: M Population Size: 1 Sources: |
| Irritability | Disc. AE | 2820 mg single, oral Overdose |
unhealthy, 25 n = 1 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: 25 Sex: M Population Size: 1 Sources: |
| Dizziness | 3% Disc. AE |
120 mg 1 times / day multiple, oral Recommended Dose: 120 mg, 1 times / day Route: oral Route: multiple Dose: 120 mg, 1 times / day Sources: Page: p.459 |
unhealthy, 49.9 n = 82 Health Status: unhealthy Condition: Fibromyalgia Age Group: 49.9 Sex: M+F Population Size: 82 Sources: Page: p.459 |
| Pain | 3% Disc. AE |
120 mg 1 times / day multiple, oral Recommended Dose: 120 mg, 1 times / day Route: oral Route: multiple Dose: 120 mg, 1 times / day Sources: Page: p.459 |
unhealthy, 49.9 n = 82 Health Status: unhealthy Condition: Fibromyalgia Age Group: 49.9 Sex: M+F Population Size: 82 Sources: Page: p.459 |
| Fatigue | 4% Disc. AE |
120 mg 1 times / day multiple, oral Recommended Dose: 120 mg, 1 times / day Route: oral Route: multiple Dose: 120 mg, 1 times / day Sources: Page: p.458 |
unhealthy, 51.5 n = 72 Health Status: unhealthy Condition: Fibromyalgia Age Group: 51.5 Sex: M+F Population Size: 72 Sources: Page: p.458 |
| Insomnia | 4% Disc. AE |
120 mg 1 times / day multiple, oral Recommended Dose: 120 mg, 1 times / day Route: oral Route: multiple Dose: 120 mg, 1 times / day Sources: Page: p.458 |
unhealthy, 51.5 n = 72 Health Status: unhealthy Condition: Fibromyalgia Age Group: 51.5 Sex: M+F Population Size: 72 Sources: Page: p.458 |
| Libido decreased | below serious, 1 patient | 4 mg single, oral Dose: 4 mg Route: oral Route: single Dose: 4 mg Sources: |
healthy, adult n = 83 Health Status: healthy Age Group: adult Sex: M Population Size: 83 Sources: |
| Fatigue | below serious, 2 patients | 4 mg single, oral Dose: 4 mg Route: oral Route: single Dose: 4 mg Sources: |
healthy, adult n = 83 Health Status: healthy Age Group: adult Sex: M Population Size: 83 Sources: |
| Nausea | below serious, 2 patients | 4 mg single, oral Dose: 4 mg Route: oral Route: single Dose: 4 mg Sources: |
healthy, adult n = 83 Health Status: healthy Age Group: adult Sex: M Population Size: 83 Sources: |
| Stomach discomfort | below serious, 4 patients | 4 mg single, oral Dose: 4 mg Route: oral Route: single Dose: 4 mg Sources: |
healthy, adult n = 83 Health Status: healthy Age Group: adult Sex: M Population Size: 83 Sources: |
| Decreased appetite | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Dizziness | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Headache | below serious, 19 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Nausea | below serious, 20 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Upper respiratory tract infection | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Diarrhoea | below serious, 6 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Insomnia | below serious, 6 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Influenza | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Somnolence | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Vomiting | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Fatigue | below serious, 8 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Drug abuse | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Panic attack | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Social phobia | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Syncope | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy, children|adolescents n = 117 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: children|adolescents Population Size: 117 Sources: |
| Diarrhoea | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Dizziness | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Fatigue | below serious, 16 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Hyperhidrosis | below serious, 16 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Somnolence | below serious, 16 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Constipation | below serious, 21 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Dry mouth | below serious, 33 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Nausea | below serious, 50 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Decreased appetite | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 151 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 151 Sources: |
| Ejaculation delayed | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 51 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 51 Sources: |
| Erectile dysfunction | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 51 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 51 Sources: |
| Prostate cancer | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy, elderly n = 51 Health Status: unhealthy Condition: Major Depressive Disorder Age Group: elderly Population Size: 51 Sources: |
| Bleeding | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Hepatic failure | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Hypomania | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Hyponatremia | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Mania | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Neuroleptic malignant syndrome | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Orthostatic hypotension | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Seizures | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Serotonin syndrome | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Suicidal behavior | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Suicidal ideation | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Syncope | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Urinary hesitation | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Urinary retention | Disc. AE | 60 mg 2 times / day multiple, oral Recommended Dose: 60 mg, 2 times / day Route: oral Route: multiple Dose: 60 mg, 2 times / day Sources: |
unhealthy Health Status: unhealthy Condition: Major Depressive Disorder|Generalized Anxiety Disorder Sources: |
| Abdominal pain | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hot flush | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hyperglycaemia | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hypersomnia | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hypoaesthesia | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Muscle spasms | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Therapeutic response unexpected | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Yawning | below serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Fatigue | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Headache | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Dry mouth | below serious, 12 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Constipation | below serious, 14 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Nausea | below serious, 14 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Somnolence | below serious, 14 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Abdominal distension | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Abdominal pain upper | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Ejaculation delayed | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Ejaculation disorder | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Gastrooesophageal reflux disease | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hypokalaemia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Irritability | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Lethargy | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Loss of libido | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Musculoskeletal pain | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Pain in extremity | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Paraesthesia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Pharyngolaryngeal pain | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Pollakiuria | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Stomach discomfort | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Testicular pain | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Urinary tract infection | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Vision blurred | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Insomnia | below serious, 21 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Anorexia | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Anorgasmia | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Asthenia | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Dyspepsia | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Erectile dysfunction | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Palpitations | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Pruritus | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Sedation | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Vomiting | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Libido decreased | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Nocturia | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Sleep disorder | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Decreased appetite | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hyperhidrosis | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hypertension | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Diarrhoea | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Dizziness | below serious, 9 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Diarrhoea | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hypoaesthesia oral | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Hypoaesthesia | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Myocardial infarction | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Transient ischaemic attack | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 112 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 112 Sources: |
| Dry mouth | below serious, 11 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Nausea | below serious, 14 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Abdominal pain upper | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Anorexia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Asthenia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Dysgeusia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Dyspepsia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Sinusitis | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Vomiting | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Weight increased | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Abdominal distension | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Erectile dysfunction | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Migraine | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Neck pain | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Tachycardia | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Vertigo | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Influenza | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Constipation | below serious, 6 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Somnolence | below serious, 6 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Dizziness | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Diarrhoea | below serious, 8 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Fatigue | below serious, 8 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Hyperhidrosis | below serious, 8 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Encephalopathy hypertensive | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Transient ischaemic attack | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Wrist fracture | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Osteoarthritis | serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 115 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 115 Sources: |
| Constipation | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
| Hyperhidrosis | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
| Dry mouth | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
| Nausea | below serious, 9 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
| Gastrointestinal disorder (NOS) | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
| Sinus infection | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 20 Health Status: unhealthy Condition: Depression Population Size: 20 Sources: |
| Vomiting | below serious, 12 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Decreased appetite | below serious, 13 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Hot flush | below serious, 13 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Somnolence | below serious, 15 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Hyperhidrosis | below serious, 23 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Insomnia | below serious, 24 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Fatigue | below serious, 25 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Dizziness | below serious, 26 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Diarrhoea | below serious, 27 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Dry mouth | below serious, 31 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Constipation | below serious, 35 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Headache | below serious, 45 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Nausea | below serious, 83 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Intervertebral disc protrusion | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 263 Health Status: unhealthy Condition: Fibromyalgia Population Size: 263 Sources: |
| Dizziness | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Somnolence | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Constipation | below serious, 12 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Dry mouth | below serious, 13 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Asthenia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Confusional state | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Decreased appetite | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Ejaculation disorder | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Hypertransaminasaemia | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Increased appetite | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Joint sprain | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Migraine | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Muscle spasms | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Neck pain | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Pruritus | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Sexual dysfunction | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Tinnitus | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Toothache | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Urinary retention | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Urine flow decreased | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Viral infection | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Vision blurred | below serious, 2 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Headache | below serious, 27 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Flatulence | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Nausea | below serious, 35 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Anorexia | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Libido decreased | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Yawning | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Hyperhidrosis | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Nasopharyngitis | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Vertigo | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Fatigue | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Diarrhoea | below serious, 9 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Acute myocardial infarction | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Alcohol poisoning | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Asthma | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Myopathy toxic | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Vertigo | serious, 1 patient | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 198 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 198 Sources: |
| Constipation | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Dry mouth | below serious, 10 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Somnolence | below serious, 12 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Dizziness | below serious, 15 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Decreased appetite | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Palpitations | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Vision blurred | below serious, 3 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Nausea | below serious, 30 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Fatigue | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Tremor | below serious, 4 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Asthenia | below serious, 5 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Anorexia | below serious, 6 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Vomiting | below serious, 6 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Abdominal discomfort | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Hyperhidrosis | below serious, 7 patients | 120 mg 1 times / day steady, oral (max) Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 108 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 108 Sources: |
| Hyperhidrosis | below serious, 10 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Vomiting | below serious, 11 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Insomnia | below serious, 13 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Somnolence | below serious, 14 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Decreased appetite | below serious, 15 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Headache | below serious, 16 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Dizziness | below serious, 17 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Diarrhoea | below serious, 18 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Fatigue | below serious, 18 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Constipation | below serious, 23 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Dry mouth | below serious, 25 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Dermatitis contact | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Dyspepsia | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Dysuria | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Feeling jittery | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Hypertension | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Liver function test abnormal | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Rash | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Thirst | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Tremor | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Urine flow decreased | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Weight increased | below serious, 3 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Abdominal pain | below serious, 4 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Dysgeusia | below serious, 4 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Hot flush | below serious, 4 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Night sweats | below serious, 4 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Palpitations | below serious, 4 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Nausea | below serious, 41 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Abdominal discomfort | below serious, 5 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Erectile dysfunction | below serious, 5 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Libido decreased | below serious, 5 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Vision blurred | below serious, 5 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Arthralgia | below serious, 6 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Cough | below serious, 6 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Flatulence | below serious, 6 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Pollakiuria | below serious, 6 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Abdominal pain upper | below serious, 7 patients | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Coronary artery disease | serious, 1 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Fall | serious, 1 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Metastases to central nervous system | serious, 1 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Syncope | serious, 1 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Urosepsis | serious, 1 patient | 120 mg 1 times / day steady, oral Dose: 120 mg, 1 times / day Route: oral Route: steady Dose: 120 mg, 1 times / day Sources: |
unhealthy n = 264 Health Status: unhealthy Condition: Osteoarthritis Population Size: 264 Sources: |
| Abdominal pain | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Acne | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Anorexia | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Aphonia | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Back pain | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Breast cyst | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Cardiac ablation | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Colonic polyp | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Confusional state | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Cystitis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Dehydration | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Drug hypersensitivity | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Dysphoria | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Epistaxis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Erectile dysfunction | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Folliculitis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Gastritis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Gastroenteritis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Generalised pruritus | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Groin pain | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Haemarthrosis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Haemorrhage vaginal | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Hyperglycaemia | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Hypersomnia | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Joint injury | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Kidney infection | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Muscle spasms | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Muscle strain | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Musculoskeletal pain | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Myalgia | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Nasal congestion | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Neurological examination abnormal | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Non-cardiac chest pain | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Osteoarthritis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Psoriasis | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Stomach discomfort | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Therapeutic response unexpected | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Tooth abscess | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Vision blurred | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Vulvovaginal pruritus | below serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Nausea | below serious, 11 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Arthralgia | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Asthma | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Conjunctivitis | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Constipation | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Irritability | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Libido decreased | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Urinary tract infection | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Vomiting | below serious, 2 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Dizziness | below serious, 3 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Dry mouth | below serious, 3 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Somnolence | below serious, 3 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Pharyngitis | below serious, 4 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Insomnia | below serious, 6 patients | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Non-cardiac chest pain | serious, 1 patient | 20 mg 1 times / day steady, oral Dose: 20 mg, 1 times / day Route: oral Route: steady Dose: 20 mg, 1 times / day Sources: |
unhealthy n = 59 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 59 Sources: |
| Pain in extremity | below serious, 10 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Contusion | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Upper respiratory tract infection | below serious, 13 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Fatigue | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Hyperhidrosis | below serious, 15 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Dizziness | below serious, 26 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Nausea | below serious, 28 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Diarrhoea | below serious, 31 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Headache | below serious, 32 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Dry mouth | below serious, 34 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Constipation | below serious, 37 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Orthostatic hypotension | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Fall | below serious, 59 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Abscess intestinal | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Ankle fracture | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Arrhythmia | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Atrial flutter | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Coronary artery occlusion | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Diabetes mellitus | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Dyspnoea | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Head injury | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Hip fracture | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Interstitial lung disease | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Intracranial aneurysm | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Oesophageal adenocarcinoma metastatic | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Orthostatic hypotension | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Osteoarthritis spinal | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Pneumoperitoneum | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Prostatitis | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Renal failure acute | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Chest pain | serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 249 Health Status: unhealthy Condition: Depression Population Size: 249 Sources: |
| Confusional state | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Lethargy | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Muscle spasms | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Nocturia | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Pharyngitis | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Pollakiuria | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Vision blurred | below serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Constipation | below serious, 10 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Diarrhoea | below serious, 10 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Insomnia | below serious, 10 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Dry mouth | below serious, 12 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Headache | below serious, 12 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Abdominal pain | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Feeling abnormal | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Libido decreased | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Myalgia | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Paraesthesia | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Pharyngolaryngeal pain | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Pharyngotonsillitis | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Sleep disorder | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Tremor | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Vomiting | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Yawning | below serious, 2 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Nausea | below serious, 24 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Anorexia | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Dyspepsia | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Erectile dysfunction | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Gastroenteritis | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Hypertension | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Pain in extremity | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Palpitations | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Sedation | below serious, 3 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Hypoaesthesia | below serious, 4 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Arthralgia | below serious, 5 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Decreased appetite | below serious, 5 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Hot flush | below serious, 5 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Somnolence | below serious, 5 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Influenza | below serious, 6 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Fatigue | below serious, 7 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Dizziness | below serious, 9 patients | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Dizziness | serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Dyspnoea | serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Muscular weakness | serious, 1 patient | 60 mg 1 times / day steady, oral (max) Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Hyperhidrosis | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Insomnia | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Fatigue | below serious, 13 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Constipation | below serious, 18 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Diarrhoea | below serious, 19 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Accidental overdose | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Somnolence | below serious, 20 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Headache | below serious, 21 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Dizziness | below serious, 22 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Blood pressure increased | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Orgasm abnormal | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Yawning | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Feeling jittery | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Libido decreased | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Tension headache | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Tremor | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Vision blurred | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Weight decreased | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Dry mouth | below serious, 40 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Abdominal pain | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Anorexia | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Restlessness | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Vomiting | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Viral upper respiratory tract infection | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Nausea | below serious, 63 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Decreased appetite | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Acute myocardial infarction | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Panic attack | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Blood creatine phosphokinase increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Vomiting | below serious, 10 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Decreased appetite | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Fatigue | below serious, 15 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Dizziness | below serious, 17 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Somnolence | below serious, 18 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Abdominal pain upper | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Influenza | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Stomach discomfort | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Tension headache | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Dry mouth | below serious, 25 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Headache | below serious, 26 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Dyspepsia | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Abnormal dreams | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Feeling jittery | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Anxiety | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Nausea | below serious, 57 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Anorgasmia | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Insomnia | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Libido decreased | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Constipation | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Hyperhidrosis | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Angina pectoris | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Sexual abuse | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Somnolence | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 154 Health Status: unhealthy Condition: Generalized Anxiety Disorder Population Size: 154 Sources: |
| Fatigue | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Insomnia | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Decreased appetite | below serious, 13 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Dizziness | below serious, 13 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Hyperhidrosis | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Diarrhoea | below serious, 15 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Constipation | below serious, 17 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Dry mouth | below serious, 22 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Somnolence | below serious, 24 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Headache | below serious, 30 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Nausea | below serious, 51 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Abdominal discomfort | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Vision blurred | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Vomiting | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Anxiety | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Dyspepsia | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Yawning | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Clostridial infection | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Diverticulitis | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Hernia inguinal | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Respiratory tract infection | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Suicide attempt | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Syncope | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 262 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 262 Sources: |
| Decreased appetite | below serious, 10 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Constipation | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Insomnia | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Dizziness | below serious, 17 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Diarrhoea | below serious, 18 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Somnolence | below serious, 22 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Dry mouth | below serious, 30 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Nausea | below serious, 46 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Fatigue | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Hyperhidrosis | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Non-cardiac chest pain | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 261 Health Status: unhealthy Condition: Depression Population Size: 261 Sources: |
| Rash | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Diarrhoea | below serious, 10 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Nausea | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Insomnia | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Dizziness | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Upper respiratory tract infection | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Erectile dysfunction | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Somnolence | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Dry mouth | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Headache | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 47 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 47 Sources: |
| Somnolence | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Vomiting | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Insomnia | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Decreased appetite | below serious, 15 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Fatigue | below serious, 17 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Constipation | below serious, 18 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Diarrhoea | below serious, 19 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Hot flush | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Muscle spasms | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Dizziness | below serious, 24 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Dry mouth | below serious, 26 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Headache | below serious, 28 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Erectile dysfunction | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Middle insomnia | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Muscle strain | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Nervousness | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Rhinorrhoea | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Sedation | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Abdominal pain upper | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Irritability | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Nightmare | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Restlessness | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Urinary tract infection bacterial | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Yawning | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Dysgeusia | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Feeling jittery | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Palpitations | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Viral upper respiratory tract infection | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Nausea | below serious, 55 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Vision blurred | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Dyspepsia | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Hyperhidrosis | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 150 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 150 Sources: |
| Menopausal symptoms | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 159 Health Status: unhealthy Condition: Fibromyalgia Population Size: 159 Sources: |
| Metrorrhagia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 159 Health Status: unhealthy Condition: Fibromyalgia Population Size: 159 Sources: |
| Abdominal pain | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Allergic rhinitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Anaemia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Arthritis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Autonomic nervous system imbalance | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Blood uric acid increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Chest discomfort | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dermatitis atopic | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Drug eruption | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dysgeusia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dyskinesia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Epistaxis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Fasciitis plantar | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Fatigue | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Folliculitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Food poisoning | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Haematocrit increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Haemoglobin increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hand-foot-and-mouth disease | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Head discomfort | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Heart rate increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Heat illness | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hordeolum | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hot flush | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hypertonic bladder | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hyperventilation | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hypoaesthesia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Keratitis bacterial | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Miliaria | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Musculoskeletal stiffness | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Myalgia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Neck mass | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Nightmare | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Nodal osteoarthritis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Oropharyngeal discomfort | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Oropharyngeal pain | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Paronychia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Periarthritis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Pertussis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Purpura | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Rash papular | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Red blood cell count increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Sensory disturbance | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Sleep paralysis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Syncope | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Synovial cyst | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Tenosynovitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Tremor | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Vitreous floaters | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Yawning | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dizziness | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Decreased appetite | below serious, 13 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Thirst | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Alanine aminotransferase increased | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Blood alkaline phosphatase increased | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Blood cholesterol increased | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Bronchitis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dizziness postural | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dyspepsia | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Feeling abnormal | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Gastritis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Herpes zoster | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hyperhidrosis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Middle insomnia | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Pollakiuria | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Pyrexia | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Trigger finger | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Upper respiratory tract infection | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Weight decreased | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Nasopharyngitis | below serious, 26 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Constipation | below serious, 29 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Contusion | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Cystitis | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dysuria | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Influenza | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Abdominal distension | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Asthenia | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Rash | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Stomatitis | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Vertigo | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Nausea | below serious, 42 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Abdominal discomfort | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Blood bilirubin increased | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Hepatic function abnormal | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Palpitations | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Pruritus | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Somnolence | below serious, 51 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Abdominal pain upper | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Vomiting | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Diarrhoea | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Headache | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Malaise | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Liver disorder | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 194 Health Status: unhealthy Condition: Fibromyalgia Population Size: 194 Sources: |
| Dizziness | below serious, 11 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Decreased appetite | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Dry mouth | below serious, 16 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Headache | below serious, 24 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Nausea | below serious, 43 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Diarrhoea | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Craniocerebral injury | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Subdural haematoma | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 207 Health Status: unhealthy Condition: Major Depressive Disorder Population Size: 207 Sources: |
| Benign prostatic hyperplasia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 116 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 116 Sources: |
| Atrophic vulvovaginitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 118 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 118 Sources: |
| Abdominal pain | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Altered saliva | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Anxiety | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Atrophic gastritis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Autoimmune thyroiditis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Blood lactate dehydrogenase increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Blood urea increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Bone contusion | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Bundle branch block right | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Carpal tunnel syndrome | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Chillblains | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Chromaturia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dysarthria | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dysphoria | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Erythema | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Excoriation | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Eye pain | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Face oedema | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Fall | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Fasciitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gastrointestinal motility disorder | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gastrooesophageal reflux disease | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gingival abscess | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gingival infection | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Haematuria | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Hot flush | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Hyperhidrosis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Hyperventilation | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Hypoaesthesia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Idiopathic thrombocytopenic purpura | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Infrequent bowel movements | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Motion sickness | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Muscle spasms | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Oedema peripheral | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Oropharyngeal pain | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Pertussis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Photophobia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Pollakiuria | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Rash macular | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Sciatica | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Sleep talking | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Spinal compression fracture | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Swelling face | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Tension headache | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Thermal burn | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Trigger finger | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Urinary retention | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Urine flow decreased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Vertigo positional | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Vomiting | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| White blood cell count increased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Decreased appetite | below serious, 10 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Thirst | below serious, 14 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dizziness | below serious, 15 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Contusion | below serious, 16 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Allergic rhinitis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Arthritis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Conjunctivitis allergic | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Conjunctivitis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Feeling abnormal | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gamma-glutamyltransferase increased | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gastritis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Hepatic function abnormal | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Large intestine polyp | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Migraine | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Nerve root injury cervical | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Sexual dysfunction | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Stomatitis | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Tachycardia | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Tinnitus | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Nausea | below serious, 21 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Constipation | below serious, 25 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Abdominal distension | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Aspartate aminotransferase increased | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Cough | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Eczema | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gastroenteritis | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Pharyngitis | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Pruritus | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Alanine aminotransferase increased | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Back pain | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Blood creatine phosphokinase increased | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dental caries | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dizziness postural | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dyspepsia | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Procedural pain | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Tremor | below serious, 4 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Somnolence | below serious, 45 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Dysuria | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Ligament sprain | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Vertigo | below serious, 5 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Liver function test abnormal | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Arthralgia | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Bronchitis | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Abdominal discomfort | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Malaise | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Diarrhoea | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Headache | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Calculus urethral | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Cerebral haemorrhage | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Gastric polyps | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| Intervertebral disc protrusion | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 234 Health Status: unhealthy Condition: Chronic Low Back Pain Population Size: 234 Sources: |
| SIADH | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 53 Health Status: unhealthy Condition: Sub-Acute Pain Population Size: 53 Sources: |
| Somnolence | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 53 Health Status: unhealthy Condition: Sub-Acute Pain Population Size: 53 Sources: |
| Nausea | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 53 Health Status: unhealthy Condition: Sub-Acute Pain Population Size: 53 Sources: |
| Abulia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Anal fissure | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Asthenia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Basedow's disease | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Blepharitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Blood potassium decreased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Cheilitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Chillblains | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Cough | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dental caries | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Depression | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dermatitis seborrhoeic | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dermatitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Diabetes mellitus | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dizziness postural | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dysgeusia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dyspepsia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Ear congestion | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Eczema | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Excoriation | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Faeces hard | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Gingival abscess | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Gingivitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Hepatic function abnormal | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Hordeolum | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Hot flush | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Hypertension | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Hypertonic bladder | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Ingrowing nail | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Limb crushing injury | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Liver function test abnormal | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Loss of consciousness | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Migraine | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Muscle injury | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Muscle rupture | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Oral herpes | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Osteoporosis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Palpitations | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Paronychia | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Peripheral swelling | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Procedural pain | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Stress urinary incontinence | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Tinnitus | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Tonsillitis | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Urethral haemorrhage | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Urinary incontinence | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Urine flow decreased | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Vertigo positional | below serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Malaise | below serious, 12 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Nausea | below serious, 18 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Constipation | below serious, 19 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Thirst | below serious, 19 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Abdominal distension | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Abdominal pain upper | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dermatitis contact | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dizziness | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Dysuria | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Intervertebral disc protrusion | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Ligament sprain | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Muscle spasms | below serious, 2 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Somnolence | below serious, 24 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Blood urine present | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Gastritis | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Insomnia | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Stomatitis | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Upper respiratory tract inflammation | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Vomiting | below serious, 3 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Diarrhoea | below serious, 6 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Aspartate aminotransferase increased | below serious, 7 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Alanine aminotransferase increased | below serious, 8 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Contusion | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Decreased appetite | below serious, 9 patients | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
| Malignant ascites | serious, 1 patient | 60 mg 1 times / day steady, oral Dose: 60 mg, 1 times / day Route: oral Route: steady Dose: 60 mg, 1 times / day Sources: |
unhealthy n = 178 Health Status: unhealthy Condition: Chronic Osteoarthritis Population Size: 178 Sources: |
Overview
| CYP3A4 | CYP2C9 | CYP2D6 | hERG |
|---|---|---|---|
OverviewOther
| Other Inhibitor | Other Substrate | Other Inducer |
|---|---|---|
Drug as perpetrator
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| likely | ||||
| likely | ||||
| likely | ||||
| likely | ||||
| moderate | yes (co-administration study) Comment: AUC of desipramine increased 3-fold Page: 8.0 |
|||
| no | ||||
| no | ||||
| no | ||||
| no | ||||
| weak [Inhibition 0.2 uM] | weak (co-administration study) Comment: concentration dependent inhibition; A six-day treatment period with DLX increased the AUC0–60, AUC0–1, and Cmax of oral administered talinolol by 11, 13, and 36%, respectively; |
Drug as victim
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| likely | ||||
| no | ||||
| yes | yes (co-administration study) Comment: concomitant use of duloxetine with fluvoxamine (CYP1A2 inhibitor) results in ~6-fold increase in AUC and ~2.5-fold increase in Cmax of duloxetine; Page: 8.0 |
|||
| yes | yes (co-administration study) Comment: Paroxetine increased the concentration of duloxetine ~60% Page: 8.0 |
Tox targets
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
PubMed
| Title | Date | PubMed |
|---|---|---|
| Can monoamine-based therapies be improved? | 2002 |
|
| [18 million sick days due to depressive illnesses. New prospects in therapy of depression]. | 2003 |
|
| [Duloxetine and other tricyclic antidepressants: pharmacodynamic effects in the lower urinary tract]. | 2003 Nov-Dec |
|
| Common pathways of depression and pain. | 2004 |
|
| [Physical recovery is part of remission]. | 2004 |
|
| Pharmacotherapy for stress urinary incontinence : present and future options. | 2004 |
|
| Newer antidepressants: review of efficacy and safety of escitalopram and duloxetine. | 2004 |
|
| The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates? | 2004 Apr |
|
| [Duloxetine in the treatment of urinary incontinence in women]. | 2004 Aug |
|
| Role of presynaptic alpha2-adrenoceptors in antidepressant action: recent findings from microdialysis studies. | 2004 Aug |
|
| Duloxetine: mechanism of action at the lower urinary tract and Onuf's nucleus. | 2004 Aug |
|
| Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine. | 2004 Aug |
|
| Metabolism of the newest antidepressants: comparisons with related predecessors. | 2004 Feb |
|
| Duloxetine vs placebo in the treatment of stress urinary incontinence: a four-continent randomized clinical trial. | 2004 Feb |
|
| Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity. | 2004 Feb 1 |
|
| [Successful phase III study with serotonin-noradrenaline reuptake inhibitor. Soon a drug to control stress incontinence]. | 2004 Feb 12 |
|
| Reboxetine: a norepinephrine selective reuptake pump inhibitor. | 2004 Jan |
|
| Duloxetine: a new approach for treating stress urinary incontinence. | 2004 Jul |
|
| Targeting serotonin and norepinephrine receptors in stress urinary incontinence. | 2004 Jul |
|
| New approaches in the pharmacological treatment of stress urinary incontinence. | 2004 Jul |
|
| The effect of previous treatment experience and incontinence severity on the placebo response of stress urinary incontinence. | 2004 Jul |
|
| Duloxetine's role in the treatment of depression and associated painful physical symptoms. | 2004 Jul |
|
| Central nervous system control of the lower urinary tract: new pharmacological approaches to stress urinary incontinence in women. | 2004 Jul |
|
| Duloxetine: an innovative approach for treating stress urinary incontinence. | 2004 Jul |
|
| Role of serotonin and noradrenaline in stress urinary incontinence. | 2004 Jul |
|
| New developments in the management of stress urinary incontinence. | 2004 Jul |
|
| Mechanisms for the inhibition of genital vascular responses by antidepressants in a female rabbit model. | 2004 Jul |
|
| Synthesis and biological activity of some known and putative duloxetine metabolites. | 2004 Jul 5 |
|
| [Update on medical treatment of female stress urinary incontinence]. | 2004 Jun |
|
| Validation of a clinical algorithm to diagnose stress urinary incontinence for large studies. | 2004 Jun |
|
| Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles. | 2004 Jun 29 |
|
| [Duloxetine and other tricyclic antidepressive agents: pharmacodynamic effects in the lower urinary tract]. | 2004 Mar |
|
| Duloxetine versus placebo in the treatment of European and Canadian women with stress urinary incontinence. | 2004 Mar |
|
| Stress urinary incontinence in women. | 2004 May |
|
| Stress incontinence: help at hand. | 2004 May |
|
| Effect of duloxetine on tolterodine pharmacokinetics in healthy volunteers. | 2004 May |
|
| [New options in the treatment of various forms of diabetic neuropathy]. | 2004 May 20 |
|
| Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats. | 2004 Nov |
|
| Preview of new drugs for overactive bladder and incontinence: darifenacin, solifenacin, trospium, and duloxetine. | 2004 Oct |
|
| Serotonin and noradrenaline reuptake inhibitors in animal models of pain. | 2004 Oct |
|
| Clinical experience with dual action antidepressants in different chronic pain syndromes. | 2004 Oct |
|
| [Pharmaceutical treatment of stress incontinence. New approaches via a direct effect of duloxetine on Onuf's nucleus]. | 2004 Oct |
|
| Duloxetine (Cymbalta): a new SNRI for depression. | 2004 Oct 11 |
|
| A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. | 2004 Sep |
|
| Balanced treatments for fibromyalgia. | 2004 Sep |
|
| Pharmacological treatment of women awaiting surgery for stress urinary incontinence. | 2004 Sep |
|
| New drugs and dosage forms. | 2004 Sep 1 |
|
| The efficacy of duloxetine: a comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials. | 2004 Sep 8 |
|
| Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents. | 2005 Feb |
|
| Comparative effects of duloxetine and desipramine on sleep EEG in healthy subjects. | 2005 Feb |
Sample Use Guides
Dosage for Treatment of Major Depressive Disorder
Administer CYMBALTA (Duloxetine) at a total dose of 40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily). For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily.
Route of Administration:
Oral
The 50% inhibitory concentration (IC50) of duloxetine for the resting and inactivated wild-type hNav1.7 Na+ channel were 22.1+/-0.4 and 1.79+/-0.10 uM, respectively. Inhibitory effects were even more pronounced when using a mammalian cell line resulting in a 34 or 59% current decrease by 10 or 30 uM duloxetine, respectively.
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NDF-RT |
N0000175749
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
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|
WHO-VATC |
QN06AX21
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
NDF-RT |
N0000000102
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
EMA ASSESSMENT REPORTS |
XERISTAR (AUTHORIZED: ANXIETY DISORDERS)
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
NCI_THESAURUS |
C265
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
EMA ASSESSMENT REPORTS |
DULOXETINE MYLAN (AUTHORIZED: ANXIETY DISORDERS)
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
EMA ASSESSMENT REPORTS |
DULOXETINE LILLY (AUTHORIZED: NEURALGIA)
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
LIVERTOX |
NBK548820
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
WHO-ATC |
N06AX21
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
EMA ASSESSMENT REPORTS |
DULOXETINE MYLAN (AUTHORIZED: NEURALGIA)
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
EMA ASSESSMENT REPORTS |
CYMBALTA (AUTHORIZED: ANXIETY DISORDERS)
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
||
|
NDF-RT |
N0000000109
Created by
admin on Fri Dec 15 16:25:41 GMT 2023 , Edited by admin on Fri Dec 15 16:25:41 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
7368
Created by
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PRIMARY | |||
|
202
Created by
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PRIMARY | |||
|
O5TNM5N07U
Created by
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PRIMARY | |||
|
O5TNM5N07U
Created by
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PRIMARY | |||
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DULOXETINE
Created by
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PRIMARY | |||
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7012
Created by
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PRIMARY | |||
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116539-59-4
Created by
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PRIMARY | |||
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DTXSID6048385
Created by
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PRIMARY | |||
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CHEMBL1175
Created by
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PRIMARY | |||
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972
Created by
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PRIMARY | |||
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C058218
Created by
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PRIMARY | |||
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100000085247
Created by
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PRIMARY | |||
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72625
Created by
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PRIMARY | RxNorm | ||
|
C65495
Created by
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PRIMARY | |||
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36795
Created by
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PRIMARY | |||
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60835
Created by
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PRIMARY | |||
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DB00476
Created by
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PRIMARY | |||
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m4782
Created by
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PRIMARY | Merck Index | ||
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Duloxetine
Created by
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SUB06424MIG
Created by
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PRIMARY |
ACTIVE MOIETY
METABOLITE (PARENT)
METABOLITE (PARENT)
METABOLITE (PARENT)
METABOLITE INACTIVE (PARENT)
METABOLITE INACTIVE (PARENT)
METABOLITE INACTIVE (PARENT)
SALT/SOLVATE (PARENT)
