Dihydroxyacetone

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H6O3
Molecular Weight	90.0779
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCC(=O)CO

InChI

InChIKey=RXKJFZQQPQGTFL-UHFFFAOYSA-N

InChI=1S/C3H6O3/c4-1-3(6)2-5/h4-5H,1-2H2

HIDE SMILES / InChI

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
sunburn 5 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4e1d19e1-eef7-45d5-b250-8426a5488317	Inactive ingredient		Approved 8583	ALMAY HEALTH GLOW 3-1 SELF TANNER Approved Use Helps prevent sunburn. If used as directed with other sun protection measures, decreases the risk of skin cancer and early skin aging caused by the sun Launch Date 2016

PubMed

Title	Date	PubMed
The crystal structure of the allosteric non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeum Thermoproteus tenax.	2002-05-31	11842090
Thermodynamic analysis of the emergence of new regulatory properties in a phosphoribulokinase-glyceraldehyde 3-phosphate dehydrogenase complex.	2002-04-12	11815615
Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.	2002-04-05	11821387
Detection, quantitation, purification, and identification of cardiac proteins S-thiolated during ischemia and reperfusion.	2002-03-22	11777920
Reaction of folic acid with reducing sugars and sugar degradation products.	2002-03-13	11879051
Phospholipase D2 directly interacts with aldolase via Its PH domain.	2002-03-12	11876650
A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role.	2002-03-08	11756459
Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.	2002-03	11872664
Inhibition of the mitochondrial permeability transition by aldehydes.	2002-02-22	11846392
Biosynthesis of d-arabinose in Mycobacterium smegmatis: specific labeling from d-glucose.	2002-02-15	11831854
The influence of temperature, salt and pH on the inhibitory effect of reuterin on Escherichia coli.	2002-02-05	11845821
Metabolism of D-[1-(13)C]fructose, D-[2-(13)C]fructose, and D-[6-(13)C]fructose in rat hepatocytes incubated in the presence of H(2)O or D(2)O.	2002-02	11855935
Chemiluminescent assay of alkaline phosphatase using dihydroxyacetone phosphate as substrate detected with lucigenin.	2002-01-30	11816056
Advanced glycation end products-induced apoptosis and overexpression of vascular endothelial growth factor in bovine retinal pericytes.	2002-01-25	11798169
Role of substrates in the regulation of mitochondrial function in situ.	2002-01-19	11798036
HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors.	2002-01-18	11785981
A novel bifunctional molybdo-enzyme catalyzing both decarboxylation of indolepyruvate and oxidation of indoleacetaldehyde from a thermoacidophilic archaeon, Sulfolobus sp. strain 7.	2002-01-16	11801253
A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli.	2002-01-11	11779234
Carbonaceous meteorites as a source of sugar-related organic compounds for the early Earth.	2002-01-10	11780054
Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.	2002-01	11744604
Digital analysis of cDNA abundance; expression profiling by means of restriction fragment fingerprinting.	2002	11882253
Significance of two distinct types of tryptophan synthase beta chain in Bacteria, Archaea and higher plants.	2002	11806827
Expression of the MTA1 mRNA in thymoma patients.	2001-12-28	11689291
AI-based algorithms for protein surface comparisons.	2001-12	11765855
Vascular endothelial growth factor mRNA in eutopic and ectopic endometrium.	2001-12	11730754
Crystal structure of the non-regulatory A(4 )isoform of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase complexed with NADP.	2001-11-30	11846565
Biosynthesis of vitamin B(6) in yeast: incorporation pattern of glucose.	2001-11-21	11707109
Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate.	2001-11-20	11705376
Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase.	2001-11-14	11697989
Cyclic AMP affinity purification and ESI-QTOF MS-MS identification of cytosolic glyceraldehyde 3-phosphate dehydrogenase and two nucleoside diphosphate kinase isoforms from tobacco BY-2 cells.	2001-11-09	11707271
Convenient and rapid ribonuclease protection assay for use with primary cell cultures.	2001-11	11730027
Engineered nonphosphorylating glyceraldehyde 3-phosphate dehydrogenase at position 268 binds hydroxylamine and hydrazine as acyl acceptors.	2001-11	11722561
Sources of blood glycerol during fasting.	2001-11	11595656
Thiol/disulfide interconversion in bovine lens aldose reductase induced by intermediates of glutathione turnover.	2001-10-09	11580274
Skin pigmentation enhancers.	2001-10	11684462
Effects of leptin on the differentiation and metabolism of human adipocytes.	2001-10	11673767
Heat treatment adaptations in Clostridium perfringens vegetative cells.	2001-10	11601701
The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates.	2001-10	11578926
Structure-activity relationships of apio nucleosides as potential antiviral agents.	2001-09-21	11563085
In vivo formation of Maillard reaction free radicals in mouse skin.	2001-09	11564185
Glyceraldehyde-3-phosphate dehydrogenase is negatively regulated by ADP-ribosylation in the fungus Phycomyces blakesleeanus.	2001-09	11535798
Structural and kinetic modifications of aldose reductase by S-nitrosothiols.	2001-08-15	11485558
Cleaving of ketosubstrates by transketolase and the nature of the products formed.	2001-08	11566066
Thermodynamics of the folding of D-glyceraldehyde-3-phosphate dehydrogenase assisted by protein disulfide isomerase studied by microcalorimetry.	2001-08	11488911
Allosteric activation of pyruvate kinase via NAD+ in rat liver cells.	2001-07	11453987
ICI 182,780 acts as a partial agonist and antagonist of estradiol effects in specific cells of the sheep uterus.	2001-06	11457666
Mechanistic imperatives for aldose-ketose isomerization in water: specific, general base- and metal ion-catalyzed isomerization of glyceraldehyde with proton and hydride transfer.	2001-02-07	11456612
Generation of choline for acetylcholine synthesis by phospholipase D isoforms.	2001	11734063
Dihydroxyacetone in a new formulation--a powerful therapeutic option in vitiligo.	2001	11701979
Reduction of human blood O2 affinity using dihydroxyacetone, phosphate, and pyruvate.	1979-09	118143

Patents

Name

Type

Language

Dihydroxyacetone

Official Name

English

FEMA NO. 4033

Preferred Name

English

DIHYDROXYACETONE [FHFI]

Common Name

English

DIHYDROXYACETONE [USP-RS]

Common Name

English

Dihydroxyacetone [WHO-DD]

Common Name

English

DIHYDROXYACETONE [USP MONOGRAPH]

Common Name

English

DIHYDROXYACETONE [HSDB]

Common Name

English

1,3-DIHYDROXY-2-PROPANONE

Systematic Name

English

DIHYDROXYACETONE [MART.]

Common Name

English

NSC-24343

Code

English

GLYCERONE

Systematic Name

English

1,3-DIHYDROXYACETONE

Systematic Name

English

DIHYDROXYACETONE [VANDF]

Common Name

English

DIHYDROXYACETONE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C344