Rapirosiran Sodium

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

AD-288996 SODIUM

Preferred Name

English

Rapirosiran Sodium

Official Name

English

RNA, (Am-sp-(2?-deoxy-2?-fluoro)G-sp-Am-Um-Am-Gm-(3??3?)-[1-de-?-D-ribofuranosyl-1-[(2S)-2,3-dihydroxypropyl]]m5U-(2??5?)-Cm-Cm-Am-Um-Gm-Cm-(2?-deoxy-2?-fluoro)A-Am-(2?-deoxy-2?-fluoro)A-Am-Gm-Cm-Am-Um-sp-Um-sp-Cm), sodium salt, complex with RNA (Am-sp-U

Common Name

English

RAPIROSIRAN SODIUM [USAN]

Common Name

English

ALN-288996 SODIUM

Code

English

[(2S,4R)-1-{1-[(2-acetamido-2-deoxy-?-D-galactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2- acetamido-2-deoxy-?-D-galactopyranosyl)oxy]pentanamido}propyl)amino]-3-oxopropoxy}methyl)-5,11,18-trioxo-14-oxa-6,10,17- triazanonacosan-29-oyl}-4-hydroxypyrrolidin-2-

Common Name

English

ALN-HSD SODIUM

Code

English

Code System Code Type Description

CAS

2755197-77-2

Created by admin on Wed Apr 02 11:39:47 GMT 2025 , Edited by admin on Wed Apr 02 11:39:47 GMT 2025

PRIMARY

USAN

KL-192

Created by admin on Wed Apr 02 11:39:47 GMT 2025 , Edited by admin on Wed Apr 02 11:39:47 GMT 2025

PRIMARY

SMS_ID

300000050817

Created by admin on Wed Apr 02 11:39:47 GMT 2025 , Edited by admin on Wed Apr 02 11:39:47 GMT 2025

PRIMARY

FDA UNII

NZ52LD879F

Created by admin on Wed Apr 02 11:39:47 GMT 2025 , Edited by admin on Wed Apr 02 11:39:47 GMT 2025

PRIMARY

NCI_THESAURUS

C199100

Created by admin on Wed Apr 02 11:39:47 GMT 2025 , Edited by admin on Wed Apr 02 11:39:47 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_1;1_3-1_13;1_15;1_17-1_23;2_1-2_6;2_8;2_12-2_21	37 / 44
2'-Fluoro-Ribose	1_2;1_14;1_16;2_7;2_9-2_11	7 / 44

Linkage	Site Range	Site Count
	1_4-1_21;2_4-2_21	36 / 42
Sodium Phosporothioate	1_2-1_3;1_22-1_23;2_2-2_3	6 / 42

ACTIVE MOIETY


					F3NU7CDG3E

SUBSTANCE RECORD


					NZ52LD879F

Rapirosiran Sodium