U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Name Type Language
Rapirosiran Sodium
USAN  
Official Name English
RNA, (Am-sp-(2′-deoxy-2′-fluoro)G-sp-Am-Um-Am-Gm-(3′→3′)-[1-de-β-D-ribofuranosyl-1-[(2S)-2,3-dihydroxypropyl]]m5U-(2′→5′)-Cm-Cm-Am-Um-Gm-Cm-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)A-Am-Gm-Cm-Am-Um-sp-Um-sp-Cm), sodium salt,
Common Name English
RAPIROSIRAN SODIUM [USAN]
Common Name English
AD-288996 SODIUM
Code English
ALN-288996 SODIUM
Code English
[(2S,4R)-1-{1-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2- acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}propyl)amino]-3-oxopropoxy}methyl)-5,11,18-trioxo-14-oxa-6,10,17- triazanonacosan-29-oyl}-4-hydroxypyrrolidin-
Common Name English
ALN-HSD SODIUM
Code English
Code System Code Type Description
CAS
2755197-77-2
Created by admin on Sat Dec 16 18:35:30 GMT 2023 , Edited by admin on Sat Dec 16 18:35:30 GMT 2023
PRIMARY
USAN
KL-192
Created by admin on Sat Dec 16 18:35:30 GMT 2023 , Edited by admin on Sat Dec 16 18:35:30 GMT 2023
PRIMARY
FDA UNII
NZ52LD879F
Created by admin on Sat Dec 16 18:35:30 GMT 2023 , Edited by admin on Sat Dec 16 18:35:30 GMT 2023
PRIMARY
NCI_THESAURUS
C199100
Created by admin on Sat Dec 16 18:35:30 GMT 2023 , Edited by admin on Sat Dec 16 18:35:30 GMT 2023
PRIMARY
Sugar Site Range Site Count
2'-O-Methyl-Ribose 1_1;1_3-1_13;1_15;1_17-1_23;2_1-2_6;2_8;2_12-2_21 37 / 44
2'-Fluoro-Ribose 1_2;1_14;1_16;2_7;2_9-2_11 7 / 44
Linkage Site Range Site Count
1_4-1_21;2_4-2_21 36 / 42
Sodium Phosporothioate 1_2-1_3;1_22-1_23;2_2-2_3 6 / 42