Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C18H23FINO2 |
Molecular Weight | 430.2861 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC[C@]([H])([C@H]([C@H](C1)C3=CC=C(I)C=C3)C(=O)OC)N2CCC[18F]
InChI
InChIKey=HXWLAJVUJSVENX-LNYNZGDVSA-N
InChI=1S/C18H23FINO2/c1-23-18(22)17-15(12-3-5-13(20)6-4-12)11-14-7-8-16(17)21(14)10-2-9-19/h3-6,14-17H,2,7-11H2,1H3/t14-,15+,16+,17-/m0/s1/i19-1
CNS Activity
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9352532 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Diagnostic | Unknown Approved UseUnknown |
PubMed
Title | Date | PubMed |
---|---|---|
Radiosynthesis of [18F] N-3-fluoropropyl-2-beta-carbomethoxy-3-beta-(4-iodophenyl) nortropane and the first human study with positron emission tomography. | 1996 Nov |
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[18F] beta-CIT-FP is superior to [11C] beta-CIT-FP for quantitation of the dopamine transporter. | 1997 Oct |
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Head-to-head comparison of (18) F-FP-CIT and (123) I-FP-CIT for dopamine transporter imaging in patients with Parkinson's disease: A preliminary study. | 2018 Jul |
Sample Use Guides
In Vivo Use Guide
Sources: https://clinicaltrials.gov/ct2/show/NCT00468078
18F-beta-CIT-FP is administered instravenously at 5mCi 90 min before PET procedure
Route of Administration:
Intravenous
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FDA ORPHAN DRUG |
451114
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NT4P0L3OCX
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186381-69-1
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11626128
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ACTIVE MOIETY