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ZAMTOCABTAGENE AUTOLEUCEL
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Official Name
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zamtocabtagene autoleucel [INN]
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Common Name
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CELLS ARE ACTIVATED IN THE PRESENCE OF A COLLOIDAL POLYMERIC NANOMATRIX COVALENTLY ATTACHED TO ANTI-CD3 AND ANTI-CD28, TRANSDUCED, AND THEN CULTURED IN THE PRESENCE OF IL-7 AND IL-15. THE T CELLS ARE PREDOMINANTLY CENTRAL MEMORY (>80%; CD4+/CD8+, CD62L+,
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Common Name
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English
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AUTOLOGOUS T CELLS OBTAINED FROM PERIPHERAL BLOOD COLLECTED BY LEUKAPHERESIS, TRANSDUCED WITH A NON-REPLICATING LENTIVIRAL VECTOR, PSEUDOTYPED WITH VESICULAR STOMATITIS VIRUS (VSV) GLYCOPROTEIN (G), ENCODING A CODON-OPTIMIZED CHIMERIC ANTIGEN RECEPTOR (C
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Common Name
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