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Details

Stereochemistry RACEMIC
Molecular Formula C18H34O3
Molecular Weight 298.4608
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYL PALMOXIRATE

SMILES

CCCCCCCCCCCCCCC1(CO1)C(=O)OC

InChI

InChIKey=RSSDZUNGAWCFPT-UHFFFAOYSA-N
InChI=1S/C18H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-18(16-21-18)17(19)20-2/h3-16H2,1-2H3

HIDE SMILES / InChI
Methyl palmoxirate, an oral hypoglycemic agent, was studied as a selective and irreversible inhibitor of the mitochondrial enzyme carnitine palmitoyltransferase and of long-chain fatty acid oxidation to treat diabetes. In addition, this compound was used to study the brain lipid metabolism by quantitative autoradiography or positron emission tomography (PET).

Approval Year

PubMed

PubMed

TitleDatePubMed
Metabolic fuels, neuropeptide Y, and estrous behavior in Syrian hamsters.
2004 May 8
Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-delta.
2006 Aug 4
Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion.
2006 Nov
Patents

Patents

Sample Use Guides

2.5 and 10 mg/kg
Route of Administration: Oral
Name Type Language
METHYL PALMOXIRATE
USAN  
USAN  
Official Name English
OXIRANECARBOXYLIC ACID, 2-TETRADECYL-, METHYL ESTER, (±)-
Common Name English
METHYL PALMOXIRATE [USAN]
Common Name English
NSC-359682
Code English
MCN-3716
Code English
Code System Code Type Description
FDA UNII
NPL6006Y4B
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY
NCI_THESAURUS
C174760
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY
ChEMBL
CHEMBL12261
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY
USAN
T-16
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY
PUBCHEM
68593
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY
CAS
69207-52-9
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY
NSC
359682
Created by admin on Fri Dec 15 18:19:54 GMT 2023 , Edited by admin on Fri Dec 15 18:19:54 GMT 2023
PRIMARY