U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C14H11F5N2O
Molecular Weight 318.242
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of DPC-082

SMILES

FC1=C(F)C2=C(NC(=O)N[C@]2(\C=C\C3CC3)C(F)(F)F)C=C1

InChI

InChIKey=JUCDJPCFPITYRP-GFUIURDCSA-N
InChI=1S/C14H11F5N2O/c15-8-3-4-9-10(11(8)16)13(14(17,18)19,21-12(22)20-9)6-5-7-1-2-7/h3-7H,1-2H2,(H2,20,21,22)/b6-5+/t13-/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1.
1999 Dec
Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors.
2000 May 18
Potency of nonnucleoside reverse transcriptase inhibitors (NNRTIs) used in combination with other human immunodeficiency virus NNRTIs, NRTIs, or protease inhibitors.
2002 Jun
Name Type Language
DPC-082
Code English
(4S)-4-((E)-2-CYCLOPROPYLVINYL)-5,6-DIFLUORO-4-(TRIFLUOROMETHYL)-1,3-DIHYDROQUINAZOLIN-2-ONE
Systematic Name English
DPC 082
Code English
2(1H)-QUINAZOLINONE, 4-((1E)-2-CYCLOPROPYLETHENYL)-5,6-DIFLUORO-3,4-DIHYDRO-4-(TRIFLUOROMETHYL)-, (4S)-
Systematic Name English
Code System Code Type Description
CAS
214287-98-6
Created by admin on Sat Dec 16 10:16:37 GMT 2023 , Edited by admin on Sat Dec 16 10:16:37 GMT 2023
PRIMARY
FDA UNII
NJZ3VH3QFS
Created by admin on Sat Dec 16 10:16:37 GMT 2023 , Edited by admin on Sat Dec 16 10:16:37 GMT 2023
PRIMARY
MANUFACTURER PRODUCT INFORMATION
DPC-082
Created by admin on Sat Dec 16 10:16:37 GMT 2023 , Edited by admin on Sat Dec 16 10:16:37 GMT 2023
PRIMARY
PUBCHEM
6451134
Created by admin on Sat Dec 16 10:16:37 GMT 2023 , Edited by admin on Sat Dec 16 10:16:37 GMT 2023
PRIMARY