OXISURAN

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H9NO2S
Molecular Weight	183.228
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[S+]([O-])CC(=O)C1=CC=CC=N1

InChI

InChIKey=DSWLRNLRVBAVFC-UHFFFAOYSA-N

InChI=1S/C8H9NO2S/c1-12(11)6-8(10)7-4-2-3-5-9-7/h2-5H,6H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/581646 | https://www.genome.jp/dbget-bin/www_bget?drug+D05305

Oxisuran was developed by Parke-Davis as an antineoplastic agent. It was shown that this drug was a differential inhibitor of cell-mediated hypersensitivity. Experiments on rodents with experimental autoimmune encephalomyelitis have revealed that oxisuran was pharmacologically effective. However, information about the further development of the compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Oxisuran and immune reactions: mediation of oxisuran action by the adrenal glands.	1975 Dec	1102602
Effect of immunosuppressive agents on human T and B lymphoblasts.	1983 Mar 1	6404281

Patents

Name

Type

Language

OXISURAN

Official Name

English

OXISURAN [USAN]

Common Name

English

oxisuran [INN]

Common Name

English

2-((METHYLSULFINYL)ACETYL)PYRIDINE

Systematic Name

English

KETONE, (METHYLSULFINYL)METHYL 2-PYRIDYL

Systematic Name

English

(Methylsulfinyl)methyl 2-pyridyl ketone

Systematic Name

English

ISMISUPREN

Common Name

English

ETHANONE, 2-(METHYLSULFINYL)-1-(2-PYRIDINYL)-

Systematic Name

English

NSC-356716

Code

English

W 6495

Code

English

(±)-ETHANONE, 2-(METHYLSULFINYL)-1-(2-PYRIDINYL)-

Systematic Name

English

W-6495

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C574