Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H14N4O2 |
| Molecular Weight | 210.2331 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN1C=NC(C(=O)NC)=C1C(=O)NC
InChI
InChIKey=RYRFAMRQBZNEPX-UHFFFAOYSA-N
InChI=1S/C9H14N4O2/c1-4-13-5-12-6(8(14)10-2)7(13)9(15)11-3/h5H,4H2,1-3H3,(H,10,14)(H,11,15)
Etimizol was developed at the Institute of Experimental Medicine, St.Petersburg USSR in 1960s. Ethymisole, or 4,5-di(N-methylcarbamoyl)-1-ethyl-imidazole, is a cognitive enhancer and nootropic drug, the molecular target of which is a multifunctional protein kinase C K2 (casein kinase II). Etimizol improves short-term memory, strengthens adrenocorticotropic function of a hypophysis; excites respiratory center.
It is indicated for the prevention of respiratory depression of various etiology, also etimizol is used for the treatment of astheno-depressive syndrome, arthritis, chronic obstructive pulmonary disease and bronchial asthma. Etimizol is marketed exclusively in Russia.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL3832943: Casein kinase 2 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Preventing | Etimizol Approved UseEtimizol is indicated for the prevention of respiratory depression of various etiology, also etimizol is used for the treatment of astheno-depressive syndrome, arthritis, chronic obstructive pulmonary disease and bronchial asthma. |
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| Primary | Etimizol Approved UseEtimizol is indicated for the prevention of respiratory depression of various etiology, also etimizol is used for the treatment of astheno-depressive syndrome, arthritis, chronic obstructive pulmonary disease and bronchial asthma. |
|||
| Primary | Etimizol Approved UseEtimizol is indicated for the prevention of respiratory depression of various etiology, also etimizol is used for the treatment of astheno-depressive syndrome, arthritis, chronic obstructive pulmonary disease and bronchial asthma. |
|||
| Primary | Etimizol Approved UseEtimizol is indicated for the prevention of respiratory depression of various etiology, also etimizol is used for the treatment of astheno-depressive syndrome, arthritis, chronic obstructive pulmonary disease and bronchial asthma. |
|||
| Primary | Etimizol Approved UseEtimizol is indicated for the prevention of respiratory depression of various etiology, also etimizol is used for the treatment of astheno-depressive syndrome, arthritis, chronic obstructive pulmonary disease and bronchial asthma. |
Sample Use Guides
In Vivo Use Guide
Sources: http://infomeds.net/etimizol.html
Orally 0,05 - 0,1 g 3 times a day after food; intravenously on 1 - 2 ml of 1,5% of solution (slowly!), intramuscularly and subcutaneously on 4 - 5 ml of 1,5% of solution. A course of treatment at mental diseases 3 - 5 weeks.
Route of Administration:
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SUBSTANCE RECORD
