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Details

Stereochemistry RACEMIC
Molecular Formula C16H17NO4.ClH
Molecular Weight 323.771
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TETRAHYDROPAPAVEROLINE HYDROCHLORIDE

SMILES

Cl.OC1=CC=C(CC2NCCC3=CC(O)=C(O)C=C23)C=C1O

InChI

InChIKey=WSIHAFYVFLJCQH-UHFFFAOYSA-N
InChI=1S/C16H17NO4.ClH/c18-13-2-1-9(6-14(13)19)5-12-11-8-16(21)15(20)7-10(11)3-4-17-12;/h1-2,6-8,12,17-21H,3-5H2;1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Some antioxidants inhibit, in a co-ordinate fashion, the production of tumor necrosis factor-alpha, IL-beta, and IL-6 by human peripheral blood mononuclear cells.
1994 Mar
Aggravation of L-DOPA-induced neurotoxicity by tetrahydropapaveroline in PC12 cells.
2003 Nov 1
Analysis of benzylisoquinoline-type alkaloids by electrospray tandem mass spectrometry and atmospheric pressure photoionization.
2005
Human white blood cells synthesize morphine: CYP2D6 modulation.
2005 Dec 1
Chiral separation of norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, and three benzoin derivatives using amino acid based molecular micelles.
2006 Feb
Norlaudanosoline and nicotine increase endogenous ganglionic morphine levels: nicotine addiction.
2006 Jul-Aug
Computational systems analysis of dopamine metabolism.
2008 Jun 18
Molecular characterization of O-methyltransferases involved in isoquinoline alkaloid biosynthesis in Coptis japonica.
2010
The biosynthesis of papaverine proceeds via (S)-reticuline.
2010 Aug
Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis.
2010 Sep
Name Type Language
TETRAHYDROPAPAVEROLINE HYDROCHLORIDE
Common Name English
DL-TETRAHYDROPAPAVEROLINE HYDROCHLORIDE
Common Name English
6,7-ISOQUINOLINEDIOL, 1-((3,4-DIHYDROXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO-, HYDROCHLORIDE (1:1)
Systematic Name English
TETRAHYDROPAPAVEROLINE (±)-FORM HYDROCHLORIDE [MI]
Common Name English
1-((3,4-DIHYDROXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROCHLORIDE
Systematic Name English
TETRAHYDROPAPAVEROLINE HYDROCHLORIDE, (±)-
Common Name English
Code System Code Type Description
MERCK INDEX
m10631
Created by admin on Sat Dec 16 08:15:56 UTC 2023 , Edited by admin on Sat Dec 16 08:15:56 UTC 2023
PRIMARY Merck Index
FDA UNII
NF7L11I15K
Created by admin on Sat Dec 16 08:15:56 UTC 2023 , Edited by admin on Sat Dec 16 08:15:56 UTC 2023
PRIMARY
CAS
3184-36-9
Created by admin on Sat Dec 16 08:15:56 UTC 2023 , Edited by admin on Sat Dec 16 08:15:56 UTC 2023
PRIMARY
EPA CompTox
DTXSID50953754
Created by admin on Sat Dec 16 08:15:56 UTC 2023 , Edited by admin on Sat Dec 16 08:15:56 UTC 2023
PRIMARY
PUBCHEM
18518
Created by admin on Sat Dec 16 08:15:56 UTC 2023 , Edited by admin on Sat Dec 16 08:15:56 UTC 2023
PRIMARY
ECHA (EC/EINECS)
221-680-7
Created by admin on Sat Dec 16 08:15:56 UTC 2023 , Edited by admin on Sat Dec 16 08:15:56 UTC 2023
PRIMARY