N-(1,3-BIS(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL)-N,N'-BIS(HYDROXYMETHYL)UREA

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H14N4O7
Molecular Weight	278.2194
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of N-(1,3-BIS(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL)-N,N'-BIS(HYDROXYMETHYL)UREA

Structure Search

SMILES

OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O

InChI

InChIKey=SOROIESOUPGGFO-UHFFFAOYSA-N

InChI=1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17725923 | https://www.ncbi.nlm.nih.gov/pubmed/19580920

Diazolidinylurea is a broad-spectrum antimicrobial preservative used in cosmetics and pharmaceutical preparations. It is especially active against gram-negative bacteria and is often combined with parabens. Diazolidinylurea is the most active member of the imidazolidinyl urea group, that acts as a formaldehyde releasers. Diazolidinylurea is used in many cosmetics, skin care products, shampoos, and conditioners, as well as a wide range of products including bubble baths, baby wipes, and household detergents.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: http://www.sunpubc.com/en/index.php?optionid=672&auto_id=300 http://www.chemicalbook.com/ChemicalProductProperty_EN_CB2158514.htm	Inactive ingredient		Approved 8429	Pain Relief Cream by ALLURE LABS INC. Approved Use Topical Analgesic Uses: For the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains and bruises. Launch Date 2017

PubMed

Title	Date	PubMed
[Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations].	2004 May	15218738
ROAT: morphology of ROAT on arm, neck and face in formaldehyde and diazolidinyl urea sensitive individuals.	2006 Jan	16426289

Name

Type

Language

N-(1,3-BIS(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL)-N,N'-BIS(HYDROXYMETHYL)UREA

Systematic Name

English

UREA, N-(1,3-BIS(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL)-N,N'-BIS(HYDROXYMETHYL)-

Systematic Name

English

N,N'-BIS(HYDROXYMETHYL)-N'-(1,3-BIS(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL)UREA

Systematic Name

English

N-HYDROXYMETHYL-N-(1,3-DI(HYDROXYMETHYL)-2,5-DIOXOIMIDAZOLIDIN-4-YL)-N'-HYDROXY-METHYLUREA

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

128971