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Details

Stereochemistry ACHIRAL
Molecular Formula Cl.Rb
Molecular Weight 120.9206
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RUBIDIUM CHLORIDE

SMILES

[Cl-].[Rb+]

InChI

InChIKey=FGDZQCVHDSGLHJ-UHFFFAOYSA-M
InChI=1S/ClH.Rb/h1H;/q;+1/p-1

HIDE SMILES / InChI

Description
Curator's Comment:: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3311597 | https://www.ncbi.nlm.nih.gov/pubmed/26442267

Rubidium chloride is an inorganic compound with the formula RbCl. It appears to be nontoxic and therapeutically effective in several types of depressive disorders. This drug develops his action on dopaminergic stimulation reducing the depressive pattern. Also radioactive rubidium-82 chloride is used as diagnostic agent in positron emission tomography (PET).

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
RUBINORM

Approved Use

Depression
PubMed

PubMed

TitleDatePubMed
Brain norepinephrine: enhanced turnover after rubidium treatment.
1970 Apr 24
Rubidium chloride ingestion by volunteer subjects: initial experience.
1971
Effects of rubidium chloride on the course of manic-depressive illness.
1978 May
Nerve fibre refractory period in patients treated with rubidium and lithium.
1978 Sep
Exploration of the clinical profile of rubidium chloride in depression: a systematic open trial.
1988 Jun
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Inhibition of HIV-1 infection by zinc group metal compounds.
1999 Sep
Gating properties of inward-rectifier potassium channels: effects of permeant ions.
2001 Nov 1
Protein kinase C-epsilon modulates mitochondrial function and active Na+ transport after oxidant injury in renal cells.
2004 Feb
Patents

Sample Use Guides

540 mg/day
Route of Administration: Oral
In Vitro Use Guide
Rubidium chloride accelerated cAMP synthesis in rat brain cortex membranes. The effect was dose-dependent and yielded above 2-fold activation of adenylate cyclase. It has been shown that Rb+ influenced directly the catalytic subunit of the enzyme and did not substitute Mg2+ in formation of the metal-ATP complex in this reaction. The stimulatory effect of Rb+ was additive to the activation of adenylate cyclase by the half-maximal (0.3 microM) as well as by the saturating (10 microM) forskolin concentrations, pointing to the fact that these effectors activate different isoforms of the enzyme in rat brain cortex.
Name Type Language
RUBIDIUM CHLORIDE
MART.   MI   WHO-DD  
Systematic Name English
NSC-84273
Code English
RBCL
Common Name English
RUBIDIUM CHLORIDE [MART.]
Common Name English
RUBIDIUM CHLORIDE [WHO-DD]
Common Name English
RUBIDIUM CHLORIDE [MI]
Common Name English
Classification Tree Code System Code
DSLD 1946 (Number of products:63)
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
Code System Code Type Description
ECHA (EC/EINECS)
232-240-9
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
EPA CompTox
7791-11-9
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
MERCK INDEX
M9687
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY Merck Index
MESH
C032710
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
FDA UNII
N3SHC5273S
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
WIKIPEDIA
RUBIDIUM CHLORIDE
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
RXCUI
1367087
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY RxNorm
CAS
7791-11-9
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
PUBCHEM
62683
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY
EVMPD
SUB15161MIG
Created by admin on Sat Jun 26 13:37:41 UTC 2021 , Edited by admin on Sat Jun 26 13:37:41 UTC 2021
PRIMARY