Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H9N3O2 |
Molecular Weight | 131.1332 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(CC(O)=O)C(N)=N
InChI
InChIKey=CVSVTCORWBXHQV-UHFFFAOYSA-N
InChI=1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)
Creatine is an amino acid that occurs in vertebrate tissues and in urine. It is synthesized mainly in the liver from three different amino acids: arginine, glycine, and methionine. In skeletal muscles, which store 95% of it, creatine generally occurs as phosphocreatine. The rest is stored in the brain, heart, and testes. Creatine functions as part of the cell's energy shuttle. It is excreted as creatinine in the urine.
Approval Year
PubMed
Title | Date | PubMed |
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Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation. | 2000 Mar-Apr |
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A dimeric creatine kinase from a sponge: implications in terms of phosphagen kinase evolution. | 2000 May |
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Evolution and physiological roles of phosphagen systems. | 2001 |
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Neuroprotective effects of MK-801 on L-2-chloropropionic acid-induced neurotoxicity. | 2001 Feb |
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Phosphorylation-dependent alteration in myofilament ca2+ sensitivity but normal mitochondrial function in septic heart. | 2001 Feb |
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Parkinsonism and neck extensor myopathy: a new syndrome or coincidental findings? | 2001 Feb |
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Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy. | 2001 Feb |
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Emergency department evaluation of chest pain using exercise stress echocardiography. | 2001 Feb |
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Mouse model of myocardial remodelling after ischemia: role of intercellular adhesion molecule-1. | 2001 Feb 1 |
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Structure of an intermediate in the unfolding of creatine kinase. | 2001 Feb 1 |
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The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip. | 2001 Feb 2 |
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Deterioration in renal function associated with fibrate therapy. | 2001 Jan |
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Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 Jan |
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Effects of EGF receptor ligands on fetal ovine myoblasts. | 2001 Jan |
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Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study. | 2001 Jan |
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Temporal lobe epilepsy: qualitative reading of 1H MR spectroscopic images for presurgical evaluation. | 2001 Jan |
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Effect of abciximab on cardiac enzyme elevation after transluminal extraction atherectomy (TEC) in high-risk saphenous vein graft lesions: comparison with a historical control group. | 2001 Jan |
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Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis. | 2001 Jan |
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Role of exercise and ascorbate on plasma antioxidant capacity in thoroughbred race horses. | 2001 Jan |
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Creatine supplementation increases renal disease progression in Han:SPRD-cy rats. | 2001 Jan |
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Validity of NIR spectroscopy for quantitatively measuring muscle oxidative metabolic rate in exercise. | 2001 Jan |
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Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts. | 2001 Jan |
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Varicella myocarditis in an adult. | 2001 Jan |
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Axonal damage in multiple sclerosis plaques: a combined magnetic resonance imaging and 1H-magnetic resonance spectroscopy study. | 2001 Jan 1 |
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Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. | 2001 Jan 20 |
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Myotoxicity studies of injectable biodegradable in-situ forming drug delivery systems. | 2001 Jan 5 |
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Assessment of coronary reperfusion in patients with myocardial infarction using fatty acid binding protein concentrations in plasma. | 2001 Mar |
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IGF-I differentially regulates Bcl-xL and Bax and confers myocardial protection in the rat heart. | 2001 Mar |
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An (1)H-MRS evaluation of the phosphocreatine/creatine pool (tCr) in human muscle. | 2001 Mar |
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Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans. | 2001 Mar |
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53074-1
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15046-6
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16687-6
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210005
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49097-9
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2148-5
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2150-1
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15047-4
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C73539
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397 (Number of products:1912)
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3123-7
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34274-1
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152701
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53055-0
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34275-8
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2149-3
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MU72812GK0
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m3826
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C37937
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MU72812GK0
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D003401
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CREATINE
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DTXSID1040451
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SUB13486MIG
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Creatine
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ACTIVE MOIETY
METABOLITE (PARENT)
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