IBOGAINE HYDROCHLORIDE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H26N2O.ClH
Molecular Weight	346.894
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[H][C@@]12C[C@H]3C[C@H](CC)[C@]1([H])[N@](C3)CCC4=C2NC5=C4C=C(OC)C=C5

InChI

InChIKey=IKJFDJLQPHDRTD-ISYVNWANSA-N

InChI=1S/C20H26N2O.ClH/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19;/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3;1H/t12-,13+,17+,20+;/m1./s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Potency
Kappa opioid receptor 108 Target ID: CHEMBL237 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959	Binding Agent 1064	2.0 µM [Ki]
Mu opioid receptor 221 Target ID: CHEMBL233 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959 \|https://www.ncbi.nlm.nih.gov/pubmed/7475926	Agonist 2678	130.0 nM [Ki]
Glutamate [NMDA] receptor 125 Target ID: CHEMBL2094124 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959	Antagonist 2778	1.0 µM [Ki]
Sigma non-opioid intracellular receptor 1 26 Target ID: Q99720\|\|\|Q7Z653 Gene ID: 10280.0 Gene Symbol: SIGMAR1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959	Binding Agent 1064	9.0 µM [Ki]
Transmembrane protein 97 11 Target ID: Q5BJF2 Gene ID: 27346.0 Gene Symbol: TMEM97 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959	Binding Agent 1064	0.09 µM [Ki]
Dopamine transporter 180 Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959	Binding Agent 1064	2.0 µM [Ki]
Serotonin transporter 178 Target ID: CHEMBL228 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26807959	Binding Agent 1064	0.5 µM [Ki]
Neuronal acetylcholine receptor; alpha3/beta4 40 Target ID: CHEMBL1907594 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20684041	Inhibitor 8297	0.95 µM [IC50]

PubMed

Title	Date	PubMed
Antimycobacterial activity of chemically defined natural substances from the Caribbean flora in Guadeloupe.	1998 Apr	9626931

Patents

Name

Type

Language

IBOGAINE HYDROCHLORIDE

Common Name

English

IBOGAINE MONOHYDROCHLORIDE

Common Name

English

IBOGAMINE, 12-METHOXY-, MONOHYDROCHLORIDE

Common Name

English

Ibogaine hydrochloride [WHO-DD]

Common Name

English

IBOGAINE, HYDROCHLORIDE

Common Name

English

IBOGAINE, MONOHYDROCHLORIDE

Common Name

English

IBOGAINE HCL

Common Name

English

IBOGAINE HYDROCHLORIDE [VANDF]

Common Name

English

IBOGAINE HYDROCHLORIDE [MI]

Common Name

English

NSC-29847

Code

English

IBOGAMINE, 12-METHOXY-, HYDROCHLORIDE (1:1)

Common Name

English

Code System Code Type Description

PUBCHEM

197059