U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H16N2O2
Molecular Weight 244.289
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIANISIDINE

SMILES

COC1=CC(=CC=C1N)C2=CC=C(N)C(OC)=C2

InChI

InChIKey=JRBJSXQPQWSCCF-UHFFFAOYSA-N
InChI=1S/C14H16N2O2/c1-17-13-7-9(3-5-11(13)15)10-4-6-12(16)14(8-10)18-2/h3-8H,15-16H2,1-2H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of oxygen, growth state, and senescence on the antioxidant responses of WI-38 fibroblasts.
2010-12
Ethyl pyruvate has anti-inflammatory and delayed myocardial protective effects after regional ischemia/reperfusion injury.
2010-11
Euphorbia peroxidase catalyzes thiocyanate oxidation in two different ways, the distal calcium ion playing an essential role.
2010-10-12
Non-linear effects of macromolecular crowding on enzymatic activity of multi-copper oxidase.
2010-04
Directed evolution of copper nitrite reductase to a chromogenic reductant.
2010-03
Optimization of media components for laccase production by litter dwelling fungal isolate Fusarium incarnatum LD-3.
2010-02
Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos.
2010
[New approaches to the measurement of the concentration and peroxidase activity of myeloperoxidase in human blood plasma].
2009-11-17
Serum ceruloplasmin oxidase activity is a sensitive and highly specific diagnostic marker for Wilson's disease.
2009-11
Inter-laboratory evaluation of the bioluminescent Salmonella reverse mutation assay using 10 model chemicals.
2009-09
Development of new methodologies for on-line determination of the bromate ion in samples of water subjected to ozonation treatment.
2009-07
Effect of exogenous phenols on superoxide production by extracellular peroxidase from wheat seedling roots.
2009-07
Effect of Zofenopril on regeneration of sciatic nerve crush injury in a rat model.
2009-06-09
Effect of zinc ion on peroxidase activity of serum in cow.
2008-11-15
Sequential and simultaneous determination of bromate and chlorite (DBPs) by flow techniques: kinetic differentiation.
2008-08-15
Metabolic adaptations to ammonia-induced oxidative stress in leaves of the submerged macrophyte Vallisneria natans (Lour.) Hara.
2008-04-28
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
2008-04
Hemozymes peroxidase activity of artificial hemoproteins constructed from the Streptomyces lividans xylanase A and iron(III)-carboxy-substituted porphyrins.
2008-04
Improved analytical sensitivity reveals the occurrence of gender-related variability in diamine oxidase enzyme activity in healthy individuals.
2007-11
Decolorisation and detoxification of Direct Blue-15 by a bacterial consortium.
2007-11
Evidence that 4-aminobiphenyl, benzidine, and benzidine congeners produce genotoxicity through reactive oxygen species.
2007-06
Glutamic acid-141: a heme 'bodyguard' in anionic tobacco peroxidase.
2007-04
Antioxidant enzymes during hypoxia-anoxia signaling events in Crocus sativus L. corm.
2006-12
A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo.
2006-11-15
Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.
2006-07
[Mechanisms of peroxidase oxidation of o-dianisidine, 3,3',5,5'-tetramethylbenzidine, and o-phenylenediamine in the presence of sodium dodecyl sulfate].
2006-03-10
Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment.
2006-03
Characterization of peroxidase in buckwheat seed.
2006-02
A new automated colorimetric method for measuring total oxidant status.
2005-12
Hollow gold nanoparticles encapsulating horseradish peroxidase.
2005-11
Precise method for the measurement of catalase activity in honey.
2005-07-09
Enzymes in the cavity of hollow silica nanoparticles.
2005-04-01
LC-MS/MS method for the confirmatory determination of aromatic amines and its application in textile analysis.
2005-01
Chemical-induced atrial thrombosis in NTP rodent studies.
2005
DNA sensor for o-dianisidine.
2004-08
Oxidation of benzidine and its derivatives by thyroid peroxidase.
2004-02
A novel automated method to measure total antioxidant response against potent free radical reactions.
2004-02
Dyes metabolized to 3,3'-dimethoxybenzidine (3,3'-dimethoxybenzidine dye class).
2004
3,3'-Dimethoxybenzidine.
2004
Spectrophotometric determination of leukocytes in urine.
2004
[Effect of temperature on structure and functional properties of horseradish peroxidase].
2003-10-28
Simplified method to assay total plasma peroxidase activity and ferriheme products in sickle cell anemia, with initial results in assessing clinical severity in a trial with citrulline therapy.
2003-10
Synthesis and evaluation of analogues of Congo red as potential compounds against transmissible spongiform encephalopathies.
2003-06
Optimisation of the enzyme-based determination of hydrogen peroxide using the quartz crystal microbalance.
2002-09
New human myelodysplastic cell line, TER-3: G-CSF specific downregulation of Ca2+/calmodulin-dependent protein kinase IV.
2002-05
Dyes metabolized to 3,3'-dimethoxybenzidine (3,3'-dimethoxybenzidine dye class).
2002
3,3'-Dimethoxybenzidine.
2002
Spectrophotometric determination of leukocytes in blood.
2002
o-Dianisidine: a new reagent for selective spectrophotometric, flow injection determination of chlorine.
2001-11
Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.
1996-12
Patents
Name Type Language
3,3'-DIMETHOXYBENZIDINE
HSDB  
Preferred Name English
DIANISIDINE
MI  
Common Name English
3,3'-DIMETHOXY-4,4'-DIAMINOBIPHENYL
Systematic Name English
DIANISIDINE [MI]
Common Name English
DIMETHOXYBENZIDINE, 3,3'-
Systematic Name English
3,3'-DIMETHOXYBENZIDINE [HSDB]
Common Name English
NSC-3168
Code English
3,3'-DIMETHOXYBENZIDINE [IARC]
Common Name English
3,3'-DIMETHOXY-(1,1'-BIPHENYL)-4,4'-DIAMINE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C45178
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
NCI_THESAURUS C461
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
Code System Code Type Description
ECHA (EC/EINECS)
204-355-4
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
HSDB
1627
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
NSC
3168
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
CAS
119-90-4
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
SMS_ID
300000053242
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
EPA CompTox
DTXSID3025091
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
NCI_THESAURUS
C44365
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
PUBCHEM
8411
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
MERCK INDEX
m4262
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY Merck Index
MESH
D003962
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
FDA UNII
MJY508JZXV
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY
WIKIPEDIA
o-Dianisidine
Created by admin on Mon Mar 31 18:42:24 GMT 2025 , Edited by admin on Mon Mar 31 18:42:24 GMT 2025
PRIMARY