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Details

Stereochemistry ACHIRAL
Molecular Formula C29H29N2S
Molecular Weight 437.619
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 1

SHOW SMILES / InChI
Structure of PRETAMAZIUM

SMILES

CC[N+]1=C(SC=C1C2=CC=C(C=C2)C3=CC=CC=C3)\C=C\C4=CC=C(C=C4)N5CCCC5

InChI

InChIKey=NNVAJWZEDBJMFG-UHFFFAOYSA-N
InChI=1S/C29H29N2S/c1-2-31-28(26-15-13-25(14-16-26)24-8-4-3-5-9-24)22-32-29(31)19-12-23-10-17-27(18-11-23)30-20-6-7-21-30/h3-5,8-19,22H,2,6-7,20-21H2,1H3/q+1

HIDE SMILES / InChI

Description
Sources: ZA 6805975; "Nematocidal 2-​(p-​dialkylaminostyryl)​-​4-​(p-​substituted-​phenyl)​thiazole alkyl halides" Phillips, Arthur Page; Burrows, Robert BZA 6805975; "Nematocidal 2-​(p-​dialkylaminostyryl)​-​4-​(p-​substituted-​phenyl)​thiazole alkyl halides" Phillips, Arthur Page; Burrows, Robert B |

Pretamazium is thiazolium derivative patented by UK pharmaceutical company Wellcome Foundation Ltd. as antiphrastic compound, that active against parasitic nematodes.

Originator

Sources: ZA 6805975; "Nematocidal 2-​(p-​dialkylaminostyryl)​-​4-​(p-​substituted-​phenyl)​thiazole alkyl halides" Phillips, Arthur Page; Burrows, Robert B.

Approval Year

Patents

Patents

Name Type Language
PRETAMAZIUM
Common Name English
4-(4-BIPHENYLYL)-3-ETHYL-2-(P-1-PYRROLIDINYLSTYRYL)THIAZOLIUM
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C250
Created by admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
Code System Code Type Description
FDA UNII
MBU80590IV
Created by admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
PRIMARY
CAS
736867-77-9
Created by admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
PRIMARY
PUBCHEM
3050425
Created by admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
PRIMARY
NCI_THESAURUS
C87626
Created by admin on Fri Dec 15 16:03:35 GMT 2023 , Edited by admin on Fri Dec 15 16:03:35 GMT 2023
PRIMARY