HEXYLGLUTATHIONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H29N3O6S
Molecular Weight	391.483
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O

InChI

InChIKey=HXJDWCWJDCOHDG-RYUDHWBXSA-N

InChI=1S/C16H29N3O6S/c1-2-3-4-5-8-26-10-12(15(23)18-9-14(21)22)19-13(20)7-6-11(17)16(24)25/h11-12H,2-10,17H2,1H3,(H,18,23)(H,19,20)(H,21,22)(H,24,25)/t11-,12-/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Ligand-induced changes in the structure and dynamics of a human class Mu glutathione S-transferase.	2000 Jun 27	10858281
Purification and characterization of a glutathione S-transferase Omega in pig: evidence for two distinct organ-specific transcripts.	2001 Aug 15	11485575
3-Methyleneoxindole: an affinity label of glutathione S-transferase pi which targets tryptophan 38.	2001 Jun 26	11412109
Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y.	2002	12112003
1.3-A resolution structure of human glutathione S-transferase with S-hexyl glutathione bound reveals possible extended ligandin binding site.	2002 Sep 1	12211029
Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione.	2003 Nov 21	12937169
Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition.	2006 Feb	16385005
Probing the mechanism of GSH activation in Schistosoma haematobium glutathione-S-transferase by site-directed mutagenesis and X-ray crystallography.	2006 Jul 14	16777141
Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1.	2008 Feb 22	18177897

Patents

Name

Type

Language

HEXYLGLUTATHIONE

Systematic Name

English

NSC-131114

Code

English

Code System Code Type Description

FDA UNII

M73SNN908F