Details
Stereochemistry | ACHIRAL |
Molecular Formula | C11H10N2O |
Molecular Weight | 186.2099 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=CC=CC(=C1)N2C=CC=CC2=O
InChI
InChIKey=ZVSGUZQJNXHNIL-UHFFFAOYSA-N
InChI=1S/C11H10N2O/c12-9-4-3-5-10(8-9)13-7-2-1-6-11(13)14/h1-8H,12H2
Amphenidone is a sedative and hypnotic drug. Aminophenidone was launched as Dornwal in April 1960 through a retail division of Wallace & Tiernan called Maltbie Laboratories. Amphenidone was a mild to moderate and safe antianxiety and antitension substance and suited
mainly for neurotic anxiety reaction. Amphenidone has also been shown to have antithyroid activity.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13685432
Curator's Comment: Rats: The amphenidone was suspended in 0.5 per cent gelatin and administered every twelve hours by stomach tube in
a total daily dose of 0.6 or 1.0 mg per g of body weight. https://www.ncbi.nlm.nih.gov/pubmed/14038388
Anxiety and tension: Ampheidone was administered orally to 40 patients, with an
average daily dose of 3700 mg (maximum
6400 mg, minimum 1600 mg) for an average period of 3 weeks. T
Route of Administration:
Oral
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C29756
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ACTIVE MOIETY