DEVAPAMIL

Details

Stereochemistry	RACEMIC
Molecular Formula	C26H36N2O3
Molecular Weight	424.5756
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=CC(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)=C1

InChI

InChIKey=VMVKIDPOEOLUFS-UHFFFAOYSA-N

InChI=1S/C26H36N2O3/c1-20(2)26(19-27,22-11-12-24(30-5)25(18-22)31-6)14-8-15-28(3)16-13-21-9-7-10-23(17-21)29-4/h7,9-12,17-18,20H,8,13-16H2,1-6H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1652439 | https://www.ncbi.nlm.nih.gov/pubmed/3656109 | DOI: 10.3390/molecules21010075 | Opie, L.H. (2012) Clinical Use of Calcium Channel Antagonist Drugs, page 232, retrieved from: https://books.google.ru/books?id=6pC4BgAAQBAJ

In the early stages of testing was shown that it is about 4 times more potent than gallopamil and 12 times more potent than verapamil in its effects on smooth muscle tone and labeled calcium uptake.

Approval Year

PubMed

Title	Date	PubMed

Name

Type

Language

DEVAPAMIL

Official Name

English

DESMETHOXYVERAPAMIL

Common Name

English

BENZENEACETONITRILE, 3,4-DIMETHOXY-.ALPHA.-(3-((2-(3-METHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-.ALPHA.-(1-METHYLETHYL)-

Systematic Name

English

2-(3,4-DIMETHOXYPHENYL)-2-ISOPROPYL-5-((M-METHOXYPHENETHYL)METHYLAMINO)VALERONITRILE

Systematic Name

English

(±)-DEVAPAMIL

Common Name

English

devapamil [INN]

Common Name

English

D 888

Code

English

DEVAPAMIL, (±)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C333