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Details

Stereochemistry RACEMIC
Molecular Formula C17H14BrFN2O2
Molecular Weight 377.208
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HALOXAZOLAM

SMILES

FC1=CC=CC=C1C23OCCN2CC(=O)NC4=CC=C(Br)C=C34

InChI

InChIKey=XDKCGKQHVBOOHC-UHFFFAOYSA-N
InChI=1S/C17H14BrFN2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22)

HIDE SMILES / InChI
Haloxazolam is a GABA-A receptor agonist indicated for the treatment of anxiety. The drug is approved and marketed in Japan under the name Somelin.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

PubMed

PubMed

TitleDatePubMed
[The behavior of 1,4-benzodiazepine drugs in the acidic media. I. Proton and carbon 13 nuclear magnetic resonance spectra of oxazolam, cloxazolam and haloxazolam in the acidic media].
1984 Jun
The behavior of 1,4-benzodiazepine drugs in acidic media. V. Kinetics of hydrolysis of flutazolam and haloxazolam in aqueous solution.
1986 Jan

Sample Use Guides

The drug is usually administered orally at bedtime at dose 5-10mg.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
HALOXAZOLAM
INN   MART.   MI   WHO-DD  
INN  
Official Name English
SOMELIN
Brand Name English
haloxazolam [INN]
Common Name English
HALOXAZOLAM [JAN]
Common Name English
HALOXAZOLAM [MI]
Common Name English
HALOXAZOLAM [MART.]
Common Name English
Haloxazolam [WHO-DD]
Common Name English
10-BROMO-11B-(O-FLUOROPHENYL)-2,3,7,11B-TETRAHYDROOXAZOLO(3,2-D)(1,4)BENZODIAZEPIN-6(5H)-ONE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1012
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
DEA NO. 2771
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
Code System Code Type Description
DRUG CENTRAL
1357
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY
EPA CompTox
DTXSID60866740
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY
PUBCHEM
3563
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY
NCI_THESAURUS
C83744
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY
WIKIPEDIA
Haloxazolam
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
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MESH
C018779
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY
MERCK INDEX
m5908
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PRIMARY Merck Index
INN
4295
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PRIMARY
DRUG BANK
DB01476
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PRIMARY
SMS_ID
100000083946
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PRIMARY
EVMPD
SUB08010MIG
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PRIMARY
ChEMBL
CHEMBL2104461
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PRIMARY
CAS
59128-97-1
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY
FDA UNII
M448L2V8XP
Created by admin on Fri Dec 15 16:52:38 GMT 2023 , Edited by admin on Fri Dec 15 16:52:38 GMT 2023
PRIMARY