BLUENSOMYCIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H39N5O14
Molecular Weight	585.5595
Optical Activity	UNSPECIFIED
Defined Stereocenters	15 / 15
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OC(N)=O)[C@@H](O)[C@@H]3NC(N)=N)O[C@@H](C)[C@]2(O)CO

InChI

InChIKey=RQLDKUSQKQMFCN-AEXVNIBOSA-N

InChI=1S/C21H39N5O14/c1-5-21(35,4-28)16(40-17-8(25-2)10(30)9(29)6(3-27)37-17)18(36-5)38-14-7(26-19(22)23)11(31)15(39-20(24)34)13(33)12(14)32/h5-18,25,27-33,35H,3-4H2,1-2H3,(H2,24,34)(H4,22,23,26)/t5-,6-,7-,8-,9-,10-,11-,12+,13+,14+,15+,16-,17-,18-,21+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5373681 | (2013) Pharmeceutical manufacturing encyclopedia, page, retrieved from: https://books.google.ru/books?id=_J2ti4EkYpkC | https://www.ncbi.nlm.nih.gov/pubmed/1698764

Bluensomycin is an aminocyclitol antibiotic obtained from cultures of Streptomyces verticillus. In vivo it has been found to be effective against experimental Staphylococcus aureus infections in mice. Preliminary tests against a variety of microorganisms of human origin revealed that bluensomycin inhibited S. aureus, Proteus mirabilis, Streptococcus (Group D), and Nocardia asteroides. Escherichia coil, Pseudomonas aeruginosa, Klebsiella pneumoniae, Candida albicans, and Aspergillus nidulans were insensitive to inhibition by bluensomycin.

Approval Year

Name

Type

Language

BLUENSOMYCIN

Official Name

English

U-12898

Preferred Name

English

bluensomycin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2363