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Details

Stereochemistry ACHIRAL
Molecular Formula C15H10O6
Molecular Weight 286.2363
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OROBOL

SMILES

OC1=CC(O)=C2C(=O)C(=COC2=C1)C3=CC=C(O)C(O)=C3

InChI

InChIKey=IOYHCQBYQJQBSK-UHFFFAOYSA-N
InChI=1S/C15H10O6/c16-8-4-12(19)14-13(5-8)21-6-9(15(14)20)7-1-2-10(17)11(18)3-7/h1-6,16-19H

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
1.24 µM [IC50]
PubMed

PubMed

TitleDatePubMed
Effect of genistein analogs on oxygen radical production in leukocytes stimulated by unopsonized zymosan.
2001 Apr
In vitro metabolism of genistein and tangeretin by human and murine cytochrome P450s.
2003 Jul
Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury.
2006 Aug 4
Characterization of mitochondria in cisplatin-resistant human ovarian carcinoma cells.
2006 Nov
The intracellular genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway.
2006 Oct 15
Red clover extract: a putative source for simultaneous treatment of menopausal disorders and the metabolic syndrome.
2008 Nov-Dec
Patents
Name Type Language
OROBOL
Common Name English
3',4',5,7-TETRAHYDROXYISOFLAVONE
Common Name English
ISOFLAVONE, 3',4',5,7-TETRAHYDROXY-
Common Name English
4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-3-(3,4-DIHYDROXYPHENYL)-
Systematic Name English
NSC-678114
Code English
ISOLUTEOLIN
Common Name English
Code System Code Type Description
CAS
480-23-9
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY
PUBCHEM
5281801
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY
EPA CompTox
DTXSID20197380
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY
WIKIPEDIA
OROBOL
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY
FDA UNII
LU8UZM1T51
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY
NSC
678114
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY
CHEBI
69437
Created by admin on Fri Dec 15 18:59:26 GMT 2023 , Edited by admin on Fri Dec 15 18:59:26 GMT 2023
PRIMARY