Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H10O6 |
Molecular Weight | 286.2363 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC(O)=C2C(=O)C(=COC2=C1)C3=CC=C(O)C(O)=C3
InChI
InChIKey=IOYHCQBYQJQBSK-UHFFFAOYSA-N
InChI=1S/C15H10O6/c16-8-4-12(19)14-13(5-8)21-6-9(15(14)20)7-1-2-10(17)11(18)3-7/h1-6,16-19H
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL4937 Sources: https://www.ncbi.nlm.nih.gov/pubmed/31222064 |
1.24 µM [IC50] | ||
Target ID: CHEMBL2021749 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30365230 |
PubMed
Title | Date | PubMed |
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Effect of genistein analogs on oxygen radical production in leukocytes stimulated by unopsonized zymosan. | 2001 Apr |
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In vitro metabolism of genistein and tangeretin by human and murine cytochrome P450s. | 2003 Jul |
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Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury. | 2006 Aug 4 |
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Characterization of mitochondria in cisplatin-resistant human ovarian carcinoma cells. | 2006 Nov |
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The intracellular genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway. | 2006 Oct 15 |
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Red clover extract: a putative source for simultaneous treatment of menopausal disorders and the metabolic syndrome. | 2008 Nov-Dec |
Patents
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480-23-9
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5281801
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DTXSID20197380
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OROBOL
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LU8UZM1T51
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678114
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69437
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SUBSTANCE RECORD