Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C18H15ClN2O3 |
Molecular Weight | 342.776 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3
InChI
InChIKey=QJERBBQXOMUURJ-INIZCTEOSA-N
InChI=1S/C18H15ClN2O3/c19-13-7-5-11(6-8-13)17(22)21-16(18(23)24)9-12-10-20-15-4-2-1-3-14(12)15/h1-8,10,16,20H,9H2,(H,21,22)(H,23,24)/t16-/m0/s1
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/6320314
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6320314
Benzotript, a cholecystokinin antagonist is an anti-gastrinic.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists. | 1981 Oct |
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Evidence that proglumide and benzotript antagonize secretagogue stimulation of isolated gastric parietal cells. | 1983 Nov |
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Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin. | 1985 May |
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Cholecystokinin antagonists proglumide, lorglumide and benzotript, but not L-364,718, interact with brain opioid binding sites. | 1990 May |
Patents
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NCI_THESAURUS |
C29701
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2060890
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C76479
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C013841
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254-500-0
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ACTIVE MOIETY