Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H19Cl2N3O4.ClH.H2O |
| Molecular Weight | 526.797 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.N[C@@H](CC1=CC(Cl)=C(OCC2=C3OC(=NC3=CC(N)=C2)C4=CC=CC=C4)C(Cl)=C1)C(O)=O
InChI
InChIKey=HGHCRNUONAQSIZ-NTEVMMBTSA-N
InChI=1S/C23H19Cl2N3O4.ClH.H2O/c24-16-6-12(8-18(27)23(29)30)7-17(25)21(16)31-11-14-9-15(26)10-19-20(14)32-22(28-19)13-4-2-1-3-5-13;;/h1-7,9-10,18H,8,11,26-27H2,(H,29,30);1H;1H2/t18-;;/m0../s1
Approval Year
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
463.1 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/32198649/ |
12 mg/m² single, intravenous dose: 12 mg/m² route of administration: Intravenous experiment type: SINGLE co-administered: |
JPH-203 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
887.8 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/32198649/ |
25 mg/m² single, intravenous dose: 25 mg/m² route of administration: Intravenous experiment type: SINGLE co-administered: |
JPH-203 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1460.5 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/32198649/ |
40 mg/m² single, intravenous dose: 40 mg/m² route of administration: Intravenous experiment type: SINGLE co-administered: |
JPH-203 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
2094.3 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/32198649/ |
60 mg/m² single, intravenous dose: 60 mg/m² route of administration: Intravenous experiment type: SINGLE co-administered: |
JPH-203 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
3022.5 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/32198649/ |
85 mg/m² single, intravenous dose: 85 mg/m² route of administration: Intravenous experiment type: SINGLE co-administered: |
JPH-203 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: UNKNOWN food status: UNKNOWN |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
2417321-16-3
Created by
admin on Wed Apr 02 19:47:41 GMT 2025 , Edited by admin on Wed Apr 02 19:47:41 GMT 2025
|
PRIMARY | |||
|
171904561
Created by
admin on Wed Apr 02 19:47:41 GMT 2025 , Edited by admin on Wed Apr 02 19:47:41 GMT 2025
|
PRIMARY | |||
|
LP8BGN8JPC
Created by
admin on Wed Apr 02 19:47:41 GMT 2025 , Edited by admin on Wed Apr 02 19:47:41 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
