Indium Chloride In-113 is a salt of the only stable Indium isotope with applications in organic synthesis as a Lewis acid. Indium Chloride is the most available soluble derivative of indium with high reproductive toxicity. In in vitro models, Indium Chloride inhibits cell viability by elevating intracellular ROS and inducing apoptosis. In animal models Indium chloride exposure cause the accumulation of indium in blood and lung, bone marrow micronucleus rate increased, the occurrence of oxidative damage and pathological changes. Besides that, the indium chloride exposed showed significant toxicity to sperm function, as well as an increased percentage of sperm morphological abnormality and chromatin DNA damage.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/28911439
Rat: 1.5 mg/kg of body weight of indium chloride, for 8 weeks, as eight intraperitoneal injections.
Route of Administration:
Intravenous
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C174673
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CHEMBL2108369
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LKY9Y8Z2EX
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admin on Sat Dec 16 06:52:49 GMT 2023 , Edited by admin on Sat Dec 16 06:52:49 GMT 2023
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All of the following components must be present:
ACTIVE MOIETY
SUBSTANCE RECORD