RPI-1

COC1=C(OC)C=C2C(NC(=O)\C2=C/C3=CC=C(O)C=C3)=C1

InChIKey=JGSMCYNBVCGIHC-QPEQYQDCSA-N

InChI=1S/C17H15NO4/c1-21-15-8-12-13(7-10-3-5-11(19)6-4-10)17(20)18-14(12)9-16(15)22-2/h3-9,19H,1-2H3,(H,18,20)/b13-7-

Targets

Primary Target	Pharmacology	Condition	Potency
Tyrosine-protein kinase receptor RET 14 Target ID: CHEMBL2041 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15240784	Inhibitor 8297

PubMed

Title	Date	PubMed
Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma.	2004 Jul 7	15240784

Name

Type

Language

RPI-1

Code

English

1,3-Dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy-2H-indol-2-one

Systematic Name

English

RPI1

Code

English

2H-Indol-2-one, 1,3-dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy-

Systematic Name

English

RPI 1 [WHO-DD]

Common Name

English

Code System Code Type Description

CAS

269730-03-2

Created by admin on Sat Dec 16 19:13:08 GMT 2023 , Edited by admin on Sat Dec 16 19:13:08 GMT 2023

PRIMARY

PUBCHEM

1749978

Created by admin on Sat Dec 16 19:13:08 GMT 2023 , Edited by admin on Sat Dec 16 19:13:08 GMT 2023

PRIMARY

FDA UNII

LJ66VPR7DB

Created by admin on Sat Dec 16 19:13:08 GMT 2023 , Edited by admin on Sat Dec 16 19:13:08 GMT 2023

PRIMARY

ACTIVE MOIETY


					LJ66VPR7DB

RPI-1