ALUMINOPARAAMINOSALICYLATE CALCIUM HYDRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C7H5NO3.Al.Ca.HO.8H2O
Molecular Weight	530.428
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ALUMINOPARAAMINOSALICYLATE CALCIUM HYDRATE

Structure Search

SMILES

O.O.O.O.O.O.O.O.[OH-].[Al+3].[Ca++].NC1=CC([O-])=C(C=C1)C([O-])=O.NC2=CC([O-])=C(C=C2)C([O-])=O

InChI

InChIKey=XWGWNNYRGUYFEE-UHFFFAOYSA-I

InChI=1S/2C7H7NO3.Al.Ca.9H2O/c2*8-4-1-2-5(7(10)11)6(9)3-4;;;;;;;;;;;/h2*1-3,9H,8H2,(H,10,11);;;9*1H2/q;;+3;+2;;;;;;;;;/p-5

HIDE SMILES / InChI

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20110106&CC=JP&NR=WO2009037855A1&KC=A1

Aluminoparaaminosalicylate calcium hydrate is antimicrobial agents and anti-inflammatory agent for topical and oral use. Para-aminosalicylic acid is an active component of Aluminoparaaminosalicylate calcium. Para-aminosalicylic acid has been shown to be a pro-drug and it is incorporated into the folate pathway by dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate a hydroxyl dihydrofolate antimetabolite, which in turn inhibits dihydrofolate reductase (DHFR) enzymatic activity.

Approval Year

Name

Type

Language

ALUMINATE(2-), BIS(4-AMINO-2-HYDROXYBENZOATO(2-)-O1,O2)AQUAHYDROXY-, CALCIUM (1:1), HEPTAHYDRATE

Preferred Name

English

ALUMINOPARAAMINOSALICYLATE CALCIUM HYDRATE

Common Name

English

ALUMINOPARAAMINOSALICYLATE CALCIUM

Common Name

English

ALUMINO P-AMINOSALICYLATE CALCIUM

Common Name

English

ALUMINOPARAAMINOSALICYLATE CALCIUM HYDRATE [JAN]

Common Name

English

Code System Code Type Description

SMS_ID

300000039653