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Details

Stereochemistry EPIMERIC
Molecular Formula C32H47F5O3S
Molecular Weight 606.771
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FULVESTRANT, 7.BETA.-

SMILES

[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]3([H])C4=C(C[C@H](CCCCCCCCC[S+]([O-])CCCC(F)(F)C(F)(F)F)[C@@]23[H])C=C(O)C=C4

InChI

InChIKey=VWUXBMIQPBEWFH-MSCODYEVSA-N
InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26+,27-,28-,29+,30-,41?/m0/s1

HIDE SMILES / InChI
Fulvestrant Beta-Isomer, also known as Fulvestrant EP Impurity A. Fulvestrant, sold under the trade name Faslodex among others, is an estrogen receptor antagonist indicated for the treatment of hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.
2009 Sep
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
FULVESTRANT, 7.BETA.-
Common Name English
7.BETA.-(9-((RS)-(4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL)NONYL)ESTRA-1,3,5(10)-TRIENE-3,17.BETA.-DIOL
Systematic Name English
FULVESTRANT IMPURITY A [EP IMPURITY]
Common Name English
FULVESTRANT .BETA.ISOMER [USP IMPURITY]
Common Name English
ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, 7-(9-((4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL)NONYL)-, (7.BETA.,17.BETA.)-
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID40193748
Created by admin on Sat Dec 16 05:14:52 GMT 2023 , Edited by admin on Sat Dec 16 05:14:52 GMT 2023
PRIMARY
PUBCHEM
71317003
Created by admin on Sat Dec 16 05:14:52 GMT 2023 , Edited by admin on Sat Dec 16 05:14:52 GMT 2023
PRIMARY
CAS
407577-53-1
Created by admin on Sat Dec 16 05:14:52 GMT 2023 , Edited by admin on Sat Dec 16 05:14:52 GMT 2023
PRIMARY
FDA UNII
L8HA5DT6RS
Created by admin on Sat Dec 16 05:14:52 GMT 2023 , Edited by admin on Sat Dec 16 05:14:52 GMT 2023
PRIMARY