BONGKREKIC ACID

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H38O7
Molecular Weight	486.5971
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	7
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CO[C@H](C\C=C/C=C/CC\C=C\C[C@H](C)\C=C\C(CC(O)=O)=C/C(O)=O)C(\C)=C/C=C(\C)C(O)=O

InChI

InChIKey=SHCXABJSXUACKU-WUTQZGRKSA-N

InChI=1S/C28H38O7/c1-21(15-18-24(19-26(29)30)20-27(31)32)13-11-9-7-5-6-8-10-12-14-25(35-4)22(2)16-17-23(3)28(33)34/h6,8-12,15-19,21,25H,5,7,13-14,20H2,1-4H3,(H,29,30)(H,31,32)(H,33,34)/b8-6+,11-9+,12-10-,18-15+,22-16-,23-17+,24-19+/t21-,25+/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.	2003 Dec 1	14678967
Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes.	2003 Nov 28	12952965
Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction.	2008 Aug	18679777
The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition.	2008 Sep 26	18667415
ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity.	2010 Jul	20412391
Bongkrekic acid as a selective activator of the peroxisome proliferator-activated receptor γ (PPARγ) isoform.	2015 Apr	25786526

Name

Type

Language

BONGKREKIC ACID

Common Name

English

BONGKREKIC ACID [MI]

Common Name

English

(-)-BONGKREKIC ACID

Common Name

English

2,4,8,10,14,18,20-DOCOSAHEPTAENEDIOIC ACID, 20-(CARBOXYMETHYL)-6-METHOXY-2,5,17-TRIMETHYL-, (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-

Systematic Name

English

Code System Code Type Description

MERCK INDEX

m2604