Details
Stereochemistry | RACEMIC |
Molecular Formula | C11H13NO3 |
Molecular Weight | 207.2258 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC(C)C(=O)C1=CC=C2OCOC2=C1
InChI
InChIKey=VKEQBMCRQDSRET-UHFFFAOYSA-N
InChI=1S/C11H13NO3/c1-7(12-2)11(13)8-3-4-9-10(5-8)15-6-14-9/h3-5,7,12H,6H2,1-2H3
Methylone (3, 4-Methylenedioxy-N-methylcathinone), a β-keto analog of 3,4-methylenedioxy-N-methylamphetamine (MDMA) is a stimulant and psychoactive drug. Methylone is a popular drug of abuse that strongly increases the release of the three monoamines: dopamine, serotonin (5-HT) and norepinephrine. In addition, methylone inhibits plasma membrane catecholamine transporters but only weakly inhibit the vesicle transporter. In April 2013, methylone was listed in the Schedule 1 substance under the Controlled Substances Act.
Approval Year
PubMed
Title | Date | PubMed |
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Methylone and mCPP, two new drugs of abuse? | 2005 Dec |
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Metabolism of the recently encountered designer drug, methylone, in humans and rats. | 2006 Aug |
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The disposition into hair of new designer drugs; methylone, MBDB and methcathinone. | 2007 Aug 15 |
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Combined intoxication with methylone and 5-MeO-MIPT. | 2007 Jan 30 |
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The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. | 2007 Mar 22 |
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[Analysis of designer drugs detected in the products purchased in fiscal year 2006]. | 2008 Oct |
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Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry. | 2010 Jun |
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Metabolism of designer drugs of abuse: an updated review. | 2010 Jun 1 |
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Head shop compound abuse amongst attendees of the Drug Treatment Centre Board. | 2010 May |
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Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse. | 2011 Dec |
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DEA NO. |
7540
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WIKIPEDIA |
Designer-drugs-Methylone
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PiHKAL
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186028-79-5
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SUB90507
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45789647
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METHYLONE
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100000140993
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C400939
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DTXSID80870167
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7997
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L4I4B1R01F
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ACTIVE MOIETY
METABOLITE (PARENT)
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