U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C11H13NO3
Molecular Weight 207.2258
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MDMC

SMILES

CNC(C)C(=O)C1=CC=C2OCOC2=C1

InChI

InChIKey=VKEQBMCRQDSRET-UHFFFAOYSA-N
InChI=1S/C11H13NO3/c1-7(12-2)11(13)8-3-4-9-10(5-8)15-6-14-9/h3-5,7,12H,6H2,1-2H3

HIDE SMILES / InChI
Methylone (3, 4-Methylenedioxy-N-methylcathinone), a β-keto analog of 3,4-methylenedioxy-N-methylamphetamine (MDMA) is a stimulant and psychoactive drug. Methylone is a popular drug of abuse that strongly increases the release of the three monoamines: dopamine, serotonin (5-HT) and norepinephrine. In addition, methylone inhibits plasma membrane catecholamine transporters but only weakly inhibit the vesicle transporter. In April 2013, methylone was listed in the Schedule 1 substance under the Controlled Substances Act.

Approval Year

PubMed

PubMed

TitleDatePubMed
Methylone and mCPP, two new drugs of abuse?
2005 Dec
Metabolism of the recently encountered designer drug, methylone, in humans and rats.
2006 Aug
The disposition into hair of new designer drugs; methylone, MBDB and methcathinone.
2007 Aug 15
Combined intoxication with methylone and 5-MeO-MIPT.
2007 Jan 30
The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain.
2007 Mar 22
[Analysis of designer drugs detected in the products purchased in fiscal year 2006].
2008 Oct
Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry.
2010 Jun
Metabolism of designer drugs of abuse: an updated review.
2010 Jun 1
Head shop compound abuse amongst attendees of the Drug Treatment Centre Board.
2010 May
Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse.
2011 Dec
Name Type Language
MDMC
Common Name English
1-PROPANONE, 1-(1,3-BENZODIOXOL-5-YL)-2-(METHYLAMINO)-
Systematic Name English
.BETA.K-MDMA
Common Name English
2-METHYLAMINO-1-(3,4-METHYLENEDIOXYPHENYL)PROPAN-1-ONE
Systematic Name English
M1 (PSYCHEDELIC)
Common Name English
METHYLENEDIOXYMETHCATHINONE
Common Name English
METHYLONE
Common Name English
J899.632F
Code English
3,4-METHYLENEDIOXY-N-METHYLCATHINONE
Systematic Name English
Classification Tree Code System Code
DEA NO. 7540
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
WIKIPEDIA Designer-drugs-Methylone
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
WIKIPEDIA PiHKAL
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
Code System Code Type Description
CAS
186028-79-5
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
EVMPD
SUB90507
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
PUBCHEM
45789647
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
WIKIPEDIA
METHYLONE
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
SMS_ID
100000140993
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
MESH
C400939
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
EPA CompTox
DTXSID80870167
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
HSDB
7997
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY
FDA UNII
L4I4B1R01F
Created by admin on Sat Dec 16 00:25:43 GMT 2023 , Edited by admin on Sat Dec 16 00:25:43 GMT 2023
PRIMARY