Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H31NO |
| Molecular Weight | 337.4983 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12[C@@H](C)CC(=C)C[C@@]13CCN(CC4CCC4)[C@@H]2CC5=CC=C(O)C=C35
InChI
InChIKey=AZJPPZHRNFQRRE-AZIXLERZSA-N
InChI=1S/C23H31NO/c1-15-10-16(2)22-21-11-18-6-7-19(25)12-20(18)23(22,13-15)8-9-24(21)14-17-4-3-5-17/h6-7,12,16-17,21-22,25H,1,3-5,8-11,13-14H2,2H3/t16-,21+,22-,23+/m0/s1
Xorphanol (also known as TR5379M) is a full κ-opioid receptor agonist and is a partial agonist at μ opioid receptor. Clinically, xorphanol was studied as an orally active analgesic that provided effective pain relief but showed low physical dependence liability. Further development of this drug was discontinued.
Originator
Approval Year
| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C241
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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NCI_THESAURUS |
C1506
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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CHEMBL2111060
Created by
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DTXSID001018240
Created by
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5488631
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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100000079361
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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C152935
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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5269
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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XORPHANOL
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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SUB00118MIG
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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77287-89-9
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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L415991P58
Created by
admin on Fri Dec 15 16:40:44 GMT 2023 , Edited by admin on Fri Dec 15 16:40:44 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
