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Details

Stereochemistry ACHIRAL
Molecular Formula C9H12N4O3
Molecular Weight 224.2166
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETOFYLLINE

SMILES

CN1C2=C(N(CCO)C=N2)C(=O)N(C)C1=O

InChI

InChIKey=NWPRCRWQMGIBOT-UHFFFAOYSA-N
InChI=1S/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3

HIDE SMILES / InChI

Description

Etofylline [7-(2-hydroxyethyl)theophylline] is a N-7-substituted derivative of theophylline, a smooth muscle relaxant. Etofylline is used to relieve bronchoconstriction. It may act as a phosphodiesterase inhibitor and adenosine receptor antagonist.

Approval Year

PubMed

PubMed

TitleDatePubMed
Prediction of genotoxicity of chemical compounds by statistical learning methods.
2005 Jun

Sample Use Guides

In Vivo Use Guide
up to 1.5 g/day
Route of Administration: oral, intravenous
Name Type Language
ETOFYLLINE
EP   INN   MART.   MI   WHO-DD  
INN  
Official Name English
7-(2-HYDROXYETHYL)THEOPHYLLINE
Systematic Name English
ETOFYLLINE [MI]
Common Name English
FREKAPHYLLIN
Common Name English
KT-200G
Code English
THEOPHYLLINE RELATED COMPOUND F
USP-RS  
Common Name English
NSC-113373
Code English
SOLUPHYLLINE
Common Name English
THEOPHYLLINE RELATED COMPOUND F [USP-RS]
Common Name English
THEOPHYLLINE IMPURITY F [EP]
Common Name English
PHYLLOCORMIN N
Common Name English
OXYPHYLLIN
Brand Name English
ETOFYLLINE [MART.]
Common Name English
ETOFYLLINE [EP]
Common Name English
7-(2-HYDROXYETHYL)-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE
Systematic Name English
ETOFYLLINE [WHO-DD]
Common Name English
ETOFYLLINE [INN]
Common Name English
Code System Code Type Description
PUBCHEM
1892
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY SWITZERF
MERCK INDEX
M5194
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY Merck Index
CAS
519-37-9
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
MESH
C008749
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
INN
1667
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
ChEMBL
CHEMBL699
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
ECHA (EC/EINECS)
208-269-8
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
EVMPD
SUB07324MIG
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
EPA CompTox
519-37-9
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY
RXCUI
24611
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY RxNorm
NCI_THESAURUS
C80611
Created by admin on Tue Mar 06 12:00:07 UTC 2018 , Edited by admin on Tue Mar 06 12:00:07 UTC 2018
PRIMARY