| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H22O6 |
| Molecular Weight | 358.3851 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@]12C[C@H](OC(=O)[C@@H]1CC[C@]3(C)[C@H]2[C@H]4OC(=O)[C@]3(O)C=C4)C5=COC=C5
InChI
InChIKey=AALLCALQGXXWNA-DURQJQQASA-N
InChI=1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13-,14-,15-,18+,19+,20+/m0/s1
Approval Year
PubMed
Patents
Sample Use Guides
In anti-canrogenesis experiments rats were fed by experimental diets, made by mixing columbin at doses of 4, 20, and 100 ppm with a powdered CE-2 basal diet. Anti-inflammatory activity was evaluated in carrageenan-induced mice paw oedema test. Columbin was intra-peritoneally administered to mice at the dose of 30, 100, 300 and 700 mg/kg.
Route of Administration:
Oral
SUBSTANCE RECORD
