AF-DX-384

Details

Stereochemistry	RACEMIC
Molecular Formula	C27H38N6O2
Molecular Weight	478.6296
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCN(CCC)CC1CCCCN1CCNC(=O)N2C3=CC=CC=C3C(=O)NC4=CC=CN=C24

InChI

InChIKey=MZDYABXXPZNUCT-UHFFFAOYSA-N

InChI=1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10,15-20H2,1-2H3,(H,29,35)(H,30,34)

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Potency
Muscarinic acetylcholine receptor M2 121 Target ID: CHEMBL211 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1941609	Antagonist 2778	1.0 nM [Kd]
Muscarinic acetylcholine receptor M4 86 Target ID: CHEMBL1821 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1941609	Antagonist 2778	2.2 nM [Kd]
Muscarinic acetylcholine receptor M3 159 Target ID: CHEMBL245 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1941609	Antagonist 2778	15.0 nM [Kd]
Muscarinic acetylcholine receptor M1 169 Target ID: CHEMBL216 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1941609	Antagonist 2778	55.0 nM [Kd]

Name

Type

Language

AF-DX-384

Code

English

AFDX 384

Code

English

11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-

Systematic Name

English

Code System Code Type Description

CAS

118290-26-9

Created by admin on Sat Dec 16 20:02:17 GMT 2023 , Edited by admin on Sat Dec 16 20:02:17 GMT 2023

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PUBCHEM

119357

Created by admin on Sat Dec 16 20:02:17 GMT 2023 , Edited by admin on Sat Dec 16 20:02:17 GMT 2023

PRIMARY

FDA UNII

KFR8EX22KX

Created by admin on Sat Dec 16 20:02:17 GMT 2023 , Edited by admin on Sat Dec 16 20:02:17 GMT 2023

PRIMARY

ACTIVE MOIETY


					KFR8EX22KX

AF-DX-384