XENAZOIC ACID

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H21NO4
Molecular Weight	375.4171
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(NC1=CC=C(C=C1)C(O)=O)C(=O)C2=CC=C(C=C2)C3=CC=CC=C3

InChI

InChIKey=BPOMPTVRBWXZBY-UHFFFAOYSA-N

InChI=1S/C23H21NO4/c1-2-28-22(24-20-14-12-19(13-15-20)23(26)27)21(25)18-10-8-17(9-11-18)16-6-4-3-5-7-16/h3-15,22,24H,2H2,1H3,(H,26,27)

HIDE SMILES / InChI

Description
Sources: (1983) Consolidated List of Products Whose Consumption And/or Sale Have Been Banned, Withdrawn, Severely Restricted Or Not Approved by Governments, page 245, retrieved from: https://books.google.ru/books?id=leVCukUgNlsC | https://www.ncbi.nlm.nih.gov/pubmed/14021836 | https://www.ncbi.nlm.nih.gov/pubmed/14419912

Xenazoic acid, an antiviral agent, was introduced in the early 1960s. Xenazoic acid might be of value in reducing the severity of meals infection if given early enough. Its use was associated with hepatic toxicity, which resulted in its withdrawal from the market in at least two countries (Belgium and France) in 1965. WHO has no information to suggest that xenazoic acid remains commercially available.

Approval Year

PubMed

Title	Date	PubMed
ANTIVIRAL ACTIVITY OF GLYOXALS AND DERIVATIVES.	1963-11	14184948
Antiviral compounds--II. Reaction of 4-biphenylglyoxal with p-aminobenzoic acid and related structures.	1960-02	13808568
New anti-viral compounds with considerable activity in vivo-I, Biphenyl derivatives.	1959-12	13808567

Sample Use Guides

In Vivo Use Guide

Single daily dose of 500 mg

Route of Administration: Oral

Name

Type

Language

XENAZOIC ACID

Official Name

English

XENOVIS

Preferred Name

English

NSC-43842

Code

English

BENZOIC ACID, P-((.ALPHA.-ETHOXY-P-PHENYLPHENACYL)AMINO)-

Systematic Name

English

CV-58903

Code

English

NSC-58991

Code

English

SKF-8318

Code

English

CV 58903

Code

English

XENAZOIC ACID [MI]

Common Name

English

xenazoic acid [INN]

Common Name

English

XANALAMINE

Common Name

English

P-((.ALPHA.-ETHOXY-P-PHENYLPHENACYL)AMINO)BENZOIC ACID

Systematic Name

English

BENZOIC ACID, 4-((2-(1,1'-BIPHENYL)-4-YL-1-ETHOXY-2-OXOETHYL)AMINO)-

Systematic Name

English

NSC-59182

Code

English

XENALAMINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281