OPINIAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H15N3O5
Molecular Weight	329.3074
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(OC)C(C(O)=O)=C(\C=N\NC(=O)C2=CC=NC=C2)C=C1

InChI

InChIKey=HSYFNANHKYNZNI-GIJQJNRQSA-N

InChI=1S/C16H15N3O5/c1-23-12-4-3-11(13(16(21)22)14(12)24-2)9-18-19-15(20)10-5-7-17-8-6-10/h3-9H,1-2H3,(H,19,20)(H,21,22)/b18-9+

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13554373 | https://www.ncbi.nlm.nih.gov/pubmed/13289818

OPINIAZIDE (also known as saluzid) was used for the treatment of meningeal tuberculosis in adults and in children. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
[Saluzide in the treatment of tuberculous meningitis in adults].	1955 Nov-Dec	13289818
[Effects of saluzide treatment on experimental tuberculous meningitis].	1955 Nov-Dec	13289821
[Saluzid content of biological fluids in meningeal tuberculosis patients; dosage of preparation; clinical and experimental research].	1957	13453403
[Saluzid in the treatment of meningeal tuberculosis in children].	1958	13554373
[A study of the effect of saluzid on the metabolism of phosphorus compounds in the liver during experimental tuberculosis with the aid of radioactive phosphorus].	1962	13911498

Patents

Name

Type

Language

OPINIAZIDE

Official Name

English

OPINIAZIDE [MI]

Common Name

English

Opiniazide [WHO-DD]

Common Name

English

opiniazide [INN]

Common Name

English

5,6-DIMETHOXYPHTHALALDEHYDIC ACID ISONICOTINOYL HYDRAZONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C280