Ozisiran

Approval Year

Name

Type

Language

Ozisiran

Official Name

English

(2RS)-3-(1,23-bis[(2-acetamido-2-deoxy-?-D-galactopyranosyl) oxy]-14-{5-[(2-acetamido-2-deoxy-?-D-galactopyranosyl) oxy]pentanoyl}-5,19-dioxo-6,10,14,18-tetraazatricosan-10-yl)-2-hydroxy-3-oxopropyl hydrogen all-Pambo-2'-O-methyl-P-thiocytidylyl-(3'?5')-

Preferred Name

English

RNA, (Cm-sp-Cm-sp-Um-Um-Gm-Am-(2?-deoxy-2?-fluoro)G-(2?-deoxy-2?-fluoro)G-(2?-deoxy-2?-fluoro)C-Am-Um-Am-Cm-Um-Um-Cm-Am-Am-Am), 3?-[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-?-D-galactopyranosyl]oxy]-1-oxopentyl][3-[[5-[[2-(acetylamino)-2-deoxy-?-D-galactopyra

Common Name

English

ozisiran [INN]

Common Name

English

Code System Code Type Description

INN

13490

Created by admin on Wed Apr 02 20:21:17 GMT 2025 , Edited by admin on Wed Apr 02 20:21:17 GMT 2025

PRIMARY

FDA UNII

K699R35T33

Created by admin on Wed Apr 02 20:21:17 GMT 2025 , Edited by admin on Wed Apr 02 20:21:17 GMT 2025

PRIMARY

CAS

3061406-96-7

Created by admin on Wed Apr 02 20:21:17 GMT 2025 , Edited by admin on Wed Apr 02 20:21:17 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_1;1_3-1_5;1_7-1_13;1_15;1_17-1_21;2_1-2_6;2_10-2_19	33 / 40
2'-Fluoro-Ribose	1_2;1_6;1_14;1_16;2_7-2_9	7 / 40

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_3;1_20-1_21;2_2-2_3	6 / 38
Phosphate	1_4-1_19;2_4-2_19	32 / 38

ACTIVE MOIETY


					K699R35T33

Ozisiran