Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C29H46O3 |
Molecular Weight | 442.6737 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@H](OC(=O)CCCCCCCCCC)[C@@]1(C)CC[C@]3([H])[C@@]4([H])CCC(=O)C=C4CC[C@@]23[H]
InChI
InChIKey=GRAAWEGTURLYKP-MVTMSODMSA-N
InChI=1S/C29H46O3/c1-3-4-5-6-7-8-9-10-11-28(31)32-27-17-16-26-25-14-12-21-20-22(30)13-15-23(21)24(25)18-19-29(26,27)2/h20,23-27H,3-19H2,1-2H3/t23-,24+,25+,26-,27-,29-/m0/s1
Nandrolone undecanoate (brand names Dynabolon) is an anabolic androgenic steroid (AAS), which had been used for the treatment of the anemia of chronic renal failure for more than 25 years. Due to concerns over adverse effects, their use historically has been limited to nandrolone decanoate given to men, usually over age 50, who have intact kidneys. It binds to the androgen receptor to a greater degree than testosterone, but due to its inability to act on the muscle in ways unmediated by the receptor, has a less overall effect on muscle growth. Despite the fact that AAS are banned substances by professional sports organizations and illegal drugs by the DEA, they are used and abused extensively, especially by teenagers and young athletes or non-athletes either for cosmetic or recreational purposes. Users may even take from 10 to 100 times higher doses than the physiological one.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: P10275 Gene ID: 367.0 Gene Symbol: AR Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/18809391 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Palliative | Unknown Approved UseUnknown |
PubMed
Title | Date | PubMed |
---|---|---|
Androgen therapy for anaemia of chronic renal failure. Indications in the erythropoietin era. | 1996 Oct |
|
Body mass reduction markedly improves muscle performance and body composition in obese females aged 61-75 years: comparison between the effects exerted by energy-restricted diet plus moderate aerobic-strength training alone or associated with rGH or nandrolone undecanoate. | 2004 Apr |
|
The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors. | 2008 Nov 13 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8936631
anemia of chronic renal failure: 200 mg per week given intramuscularly, for six months
Route of Administration:
Intramuscular
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Brand Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NCI_THESAURUS |
C2360
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
94193
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
SUB03388MIG
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
Nandrolone undecanoate
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
C95974
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
862-89-5
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
K64MCF1I9Z
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
100000085691
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
DTXSID701006644
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY | |||
|
212-729-3
Created by
admin on Fri Dec 15 18:37:45 GMT 2023 , Edited by admin on Fri Dec 15 18:37:45 GMT 2023
|
PRIMARY |
SUBSTANCE RECORD