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Details

Stereochemistry ACHIRAL
Molecular Formula C14H19N3O.C6H8O7
Molecular Weight 437.4437
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXOLAMINE CITRATE

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCC1=NC(=NO1)C2=CC=CC=C2

InChI

InChIKey=RBZIGQJSMCOHSS-UHFFFAOYSA-N
InChI=1S/C14H19N3O.C6H8O7/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-9H,3-4,10-11H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Description

Oxolamine under brand names Symphocal, Perebron is used in some countries as a cough suppressant for the treatment of pharyngitis, tracheitis, bronchitis, bronchiectasis, pertussis. Oxolamine possesses anti-inflammatory activity, which causes a reduction in the irritation of the nervous receptors of the respiratory tract.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Perebron
Palliative
Perebron
Palliative
Perebron
Palliative
Perebron

PubMed

Sample Use Guides

In Vivo Use Guide
In general, 15-25 mg per kilogram per day should be given by dividing four equal doses. In children over 2 years: 1-2 ml of 5 ml Adults: 2 ml of 5 ml 4 times daily 4 hours a day, after an equal amount of water.
Route of Administration: Oral
In Vitro Use Guide
Unknown