Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H19N3O.C6H8O7 |
| Molecular Weight | 437.4445 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(CC)CCc1nc(-c2ccccc2)no1.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChI
InChIKey=RBZIGQJSMCOHSS-UHFFFAOYSA-N
InChI=1S/C14H19N3O.C6H8O7/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-9H,3-4,10-11H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
Oxolamine under brand names Symphocal, Perebron is used in some countries as a cough suppressant for the treatment of pharyngitis, tracheitis, bronchitis, bronchiectasis, pertussis. Oxolamine possesses anti-inflammatory activity, which causes a reduction in the irritation of the nervous receptors of the respiratory tract.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effect of oxolamine on cough sensitivity in COPD patients. | 2002 Jan |
|
| Effect of oxolamine on anticoagulant effect of warfarin. | 2006 Jan 15 |
|
| Gender difference in the pharmacokinetic interaction between oral warfarin and oxolamine in rats: inhibition of CYP2B1 by oxolamine in male rats. | 2007 Apr |
Patents
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| Code System | Code | Type | Description | ||
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217-760-6
Created by
admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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1949-20-8
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16045
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SUB03576MIG
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admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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1949-20-8
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admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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K5X4XBR694
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admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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M8313
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admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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59053
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admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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C008735
Created by
admin on Fri Jun 25 22:05:19 UTC 2021 , Edited by admin on Fri Jun 25 22:05:19 UTC 2021
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ACTIVE MOIETY
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
