ANAZOCINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H23NO
Molecular Weight	245.3599
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1(C2CCCC1CN(C)C2)C3=CC=CC=C3

InChI

InChIKey=YFFNPIAPUDUYAU-UHFFFAOYSA-N

InChI=1S/C16H23NO/c1-17-11-14-9-6-10-15(12-17)16(14,18-2)13-7-4-3-5-8-13/h3-5,7-8,14-15H,6,9-12H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5528556 | https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA790&lpg=PA790&dq=ANAZOCINE retrieved from The Dictionary of Drugs: Chemical Data. Chemical Data, Structures and Bibliographies. Editors: Elks, J., p.790 | https://www.ncbi.nlm.nih.gov/pubmed/5466642 | https://www.ncbi.nlm.nih.gov/pubmed/4674739

Azabicyclane (azabicyclane) is an analgesic and antiinflammatory agent. The analgesic effect of azabicyclane has been demonstrated in mice and rats in tests using mechanical, chemical and thermal stimuli. The analgesic potency of azabicyclane was about 3-6 times greater than that of meperidine according to these testing methods.

Originator

Approval Year

PubMed

Title	Date	PubMed
7-Aza analogs of the analgetic agent azabicyclane. Synthesis and pharmacologic analysis.	1976-01	1246043
[Anesthesia with azabicyclane and nitrous oxid].	1972-10	4674739
The pharmacology of azabicyclane, a new analgesic agent.	1970-09	5528556

Patents

Sample Use Guides

In Vivo Use Guide

In rats treated with 8 mg/kg, 3 times daily, azabicyclane induced no significant loss of body weight during the withdrawal period.

Route of Administration: Other

Name

Type

Language

anazocine [INN]

Preferred Name

English

ANAZOCINE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C67413