CARBOCLORAL

Details

Stereochemistry	RACEMIC
Molecular Formula	C5H8Cl3NO3
Molecular Weight	236.481
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)NC(O)C(Cl)(Cl)Cl

InChI

InChIKey=ITMSAWKLJVGBIT-UHFFFAOYSA-N

InChI=1S/C5H8Cl3NO3/c1-2-12-4(11)9-3(10)5(6,7)8/h3,10H,2H2,1H3,(H,9,11)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13481836 | https://www.ncbi.nlm.nih.gov/pubmed/13481834 |

Carbocloral is a carbamate ester derivative used as sedative and hypnotic drug. Carbocloral is as effective as chloral hydrate in producing sedation, hypnosis, and general anesthesia, and more effective in inducing relaxation of skeletal muscles. Carbocloral was also more effective as an anticonvulsant and less toxic than chloral hydrate.

Originator

Approval Year

PubMed

Title	Date	PubMed
In silico prediction of central nervous system activity of compounds. Identification of potential pharmacophores by the TOPS-MODE approach.	2004-11-15	15498659
Prediction of properties of chiral compounds by molecular topology.	1998-02	9783256

Patents

Name

Type

Language

PRODORM

Preferred Name

English

CARBOCLORAL

Official Name

English

CN-16146

Code

English

carbocloral [INN]

Common Name

English

CARBAMIC ACID, (2,2,2-TRICHLORO-1-HYDROXYETHYL)-, ETHYL ESTER

Common Name

English

CARBOCLORAL [MI]

Common Name

English

HY-185

Code

English

CI-336

Code

English

Ethyl (2,2,2-trichloro-1-hydroxyethyl)carbamate

Systematic Name

English

CARBOCLORAL [USAN]

Common Name

English

NSC-33077

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29756