Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C13H19N3OS.C4H4O4 |
| Molecular Weight | 381.447 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)\C=C\C(O)=O.CN(C)CCC1CN(C)C(=S)C2=CC=CN=C2O1
InChI
InChIKey=LZFCSDIBLCSFAK-WLHGVMLRSA-N
InChI=1S/C13H19N3OS.C4H4O4/c1-15(2)8-6-10-9-16(3)13(18)11-5-4-7-14-12(11)17-10;5-3(6)1-2-4(7)8/h4-5,7,10H,6,8-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
Rocastine (AHR-11325) is a potent, nonsedating antihistamine with a rapid onset of action. This H1-antagonist effectively protected guinea pigs challenged with a lethal dose of histamine. It has also been mentioned in patents as a candidate to treat eye conditions and cough/cold mixtures (in which the lack of sedative effects from a non-sedating antihistamine would be especially useful in children, because daytime sedation is especially undesirable in this group). However, information on current use is not available and other second-generation, non-sedative antihistamines are available.
Approval Year
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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91833-50-0
Created by
admin on Sat Dec 16 10:14:55 GMT 2023 , Edited by admin on Sat Dec 16 10:14:55 GMT 2023
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PRIMARY | |||
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6917885
Created by
admin on Sat Dec 16 10:14:55 GMT 2023 , Edited by admin on Sat Dec 16 10:14:55 GMT 2023
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PRIMARY | |||
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1156096-60-4
Created by
admin on Sat Dec 16 10:14:55 GMT 2023 , Edited by admin on Sat Dec 16 10:14:55 GMT 2023
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NON-SPECIFIC STOICHIOMETRY | |||
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K0F56K7CMZ
Created by
admin on Sat Dec 16 10:14:55 GMT 2023 , Edited by admin on Sat Dec 16 10:14:55 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
