U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H31NO3.ClH
Molecular Weight 393.947
Optical Activity ( - )
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Aroxybutynin chloride

SMILES

Cl.CCN(CC)CC#CCOC(=O)[C@@](O)(C1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=SWIJYDAEGSIQPZ-FTBISJDPSA-N
InChI=1S/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H/t22-;/m0./s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Pharmacokinetics, metabolism, and saliva output during transdermal and extended-release oral oxybutynin administration in healthy subjects.
2003 Jun
Oxybutynin extended-release: a review of its use in the management of overactive bladder.
2004
Oxybutynin for treatment of urge urinary incontinence and overactive bladder: an updated review.
2004 Nov
Effect of controlled-release delivery on the pharmacokinetics of oxybutynin at different dosages: severity-dependent treatment of the overactive bladder.
2004 Oct
Prediction of genotoxicity of chemical compounds by statistical learning methods.
2005 Jun
New transdermal bioadhesive film containing oxybutynin: In vitro permeation across rabbit ear skin.
2006 Nov 15
Bladder augmentation: Review of the literature and recent advances.
2007 Oct
A review of urodynamic evaluation in children and its role in the management of boys with posterior urethral valves.
2007 Oct
Primary monosymptomatic nocturnal enuresis in children and adolescents.
2007 Sep
Patient perspectives in the management of overactive bladder, focus on transdermal oxybutynin.
2008 Feb 2
The neurogenic bladder: medical treatment.
2008 May
Locked-in Syndrome in a Nigerian male with Multiple Sclerosis: a case report and literature review.
2008 Oct 30
Behavioral intervention versus pharmacotherapy or their combinations in the management of overactive bladder dysfunction.
2009
No difference in between-country variability in use of newly approved orphan and non- orphan medicinal products--a pilot study.
2009 Dec 14
Trospium chloride and oxybutynin hydrochloride in a german study of adults with urinary urge incontinence: results of a 12-week, multicenter, randomized, double-blind, parallel-group, flexible-dose noninferiority trial.
2009 Nov
Oxybutynin extended release for the management of overactive bladder: a clinical review.
2009 Sep 21
Medical management of overactive bladder.
2010 Apr
Anesthetic management of the emergency laparotomy for a patient with multiple sclerosis -A case report-.
2010 Nov
Patents
Name Type Language
Aroxybutynin chloride
Common Name English
4-(diethylamino)but-2-yn-1-yl (R)-cyclohexyl(hydroxy)(phenyl)acetate hydrochloride
Systematic Name English
Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-2-butyn-1-yl ester, hydrochloride (1:1), (αR)-
Systematic Name English
OXYBUTYNIN HYDROCHLORIDE, (R)-
Common Name English
OXYBUTYNIN CHLORIDE, (R)-
Common Name English
Code System Code Type Description
PUBCHEM
11349918
Created by admin on Sat Dec 16 11:17:28 GMT 2023 , Edited by admin on Sat Dec 16 11:17:28 GMT 2023
PRIMARY
FDA UNII
JWB87T68BN
Created by admin on Sat Dec 16 11:17:28 GMT 2023 , Edited by admin on Sat Dec 16 11:17:28 GMT 2023
PRIMARY
CAS
1207344-05-5
Created by admin on Sat Dec 16 11:17:28 GMT 2023 , Edited by admin on Sat Dec 16 11:17:28 GMT 2023
PRIMARY