SECLAZONE

Details

Stereochemistry	RACEMIC
Molecular Formula	C10H8ClNO3
Molecular Weight	225.628
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC2=C(OC3CCON3C2=O)C=C1

InChI

InChIKey=XWXVKXXKKLBDDJ-UHFFFAOYSA-N

InChI=1S/C10H8ClNO3/c11-6-1-2-8-7(5-6)10(13)12-9(15-8)3-4-14-12/h1-2,5,9H,3-4H2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4761775

Seclazone was developed as a non-steroidal anti-inflammatory agent. This compound also possesses analgesic and antipyretic properties. Information about the current use of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Optimal conditions for the hydrolysis of seclazone by rat hepatic microsomes.	1974-09	4218724
The metabolic fate of seclazone in man.	1974-05	4416360
The pharmacological properties of seclazone (7-chloro-3,3a-dihydro-2H, 9H-isoxazolo (3,2-b) (1,3) benzoxazin-9-one) a new anti-inflammatory agent.	1973	4714232
The in vivo antibradykinin activity of seclazone (7-chloro-3,3a-dihydro-2H,9H-isoxazolo(3,2-b) (1,3)benzoxazin-9-one), a new anti-inflammatory agent.	1973	4761775

Name

Type

Language

SECLAZONE

Official Name

English

NSC-294833

Preferred Name

English

W-2354

Code

English

seclazone [INN]

Common Name

English

SECLAZONE [USAN]

Common Name

English

W-2352

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C921